Yu-Hung Wu1. 1. Department of Dermatology, Mackay Memorial Hospital, Mackay Medicine, Nursing and Management College, Taipei, Taiwan. yuhung_wu@yahoo.com
Abstract
BACKGROUND: Folliculosebaceous cystic hamartoma (FSCH) histologically resembles trichofolliculoma. METHODS: The clinical and histologic characteristics of both tumors were studied retrospectively, comparing these findings with those of other similar follicular tumors described in the literature. RESULTS: Fourteen cases of FSCH and 15 cases of trichofolliculoma were diagnosed over 5 years. FSCH were larger, of longer duration, located mostly in the head and neck region. Histologically, the two lesions had a similar architecture except for the presence of a secondary follicle in trichofolliculoma. CONCLUSION: FSCH are probably more common than previously thought and may be part of a spectrum of cystic follicular tumors. The perifollicular stroma may influence differentiation of the cystic wall, resulting in a variety of follicular tumors with overlapping features.
BACKGROUND:Folliculosebaceous cystic hamartoma (FSCH) histologically resembles trichofolliculoma. METHODS: The clinical and histologic characteristics of both tumors were studied retrospectively, comparing these findings with those of other similar follicular tumors described in the literature. RESULTS: Fourteen cases of FSCH and 15 cases of trichofolliculoma were diagnosed over 5 years. FSCH were larger, of longer duration, located mostly in the head and neck region. Histologically, the two lesions had a similar architecture except for the presence of a secondary follicle in trichofolliculoma. CONCLUSION: FSCH are probably more common than previously thought and may be part of a spectrum of cystic follicular tumors. The perifollicular stroma may influence differentiation of the cystic wall, resulting in a variety of follicular tumors with overlapping features.