Literature DB >> 18493961

New pentacyclic triterpenes from Gypsophila oldhamiana and their biological evaluation as glycogen phosphorylase inhibitors.

Jian-Guang Luo1, Jun Liu, Ling-Yi Kong.   

Abstract

The three new pentacyclic triterpenes 1-3 were isolated and elucidated from the roots of Gypsophila oldhamiana, together with seven known triterpenes (4-10). These triterpenes were evaluated for their glycogen phosphorylase inhibitory activity and preliminary structure-activity trends are suggested.

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Year:  2008        PMID： 18493961     DOI： 10.1002/cbdv.200890071

Source DB:  PubMed          Journal:  Chem Biodivers        ISSN： 1612-1872            Impact factor:   2.408


  5 in total

1.  Oldhamianoside inhibits the growth of ovarian cancer both in vitro and in vivo via adjusting inflammation and angiogenesis signals.

Authors:  Zenghui Li; Ying Zuo; Li Hou; Liangliang Dong; Xiaomei Sun
Journal:  Onco Targets Ther       Date:  2018-09-19       Impact factor: 4.147

Review 2.  Anti-Diabetic Potential of Plant-Based Pentacyclic Triterpene Derivatives: Progress Made to Improve Efficacy and Bioavailability.

Authors:  Michael Oboh; Laurencia Govender; Muthulisi Siwela; Blessing Nkazimulo Mkhwanazi
Journal:  Molecules       Date:  2021-11-29       Impact factor: 4.411

Review 3.  Current knowledge and development of hederagenin as a promising medicinal agent: a comprehensive review.

Authors:  Jia Zeng; Ting Huang; Man Xue; Jianxing Chen; Linglin Feng; Ruofei Du; Yi Feng
Journal:  RSC Adv       Date:  2018-07-03       Impact factor: 4.036

Review 4.  The role of triterpenes in the management of diabetes mellitus and its complications.

Authors:  J Nazaruk; M Borzym-Kluczyk
Journal:  Phytochem Rev       Date:  2014-06-24       Impact factor: 5.374

5.  Cytotoxicity of gypsogenic acid isolated from Gypsophila trichotoma.

Authors:  Ilina Krasteva; Maya Yotova; Deyan Yosifov; Niko Benbassat; Kristina Jenett-Siems; Spiro Konstantinov
Journal:  Pharmacogn Mag       Date:  2014-04       Impact factor: 1.085
  5 in total

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