Literature DB >> 18493825

Long-term outcome and risk factors of failure after bile duct injury repair.

Yaacov Goykhman1, Issac Kory, Risa Small, Ada Kessler, Joseph M Klausner, Richard Nakache, Menahem Ben-Haim.   

Abstract

BACKGROUND: The real long-term outcome of a hepaticojejunostomy (HJ) to repair bile duct injury (BDI) is unclear, and the risk factors for repair failure are partially defined. STUDY
DESIGN: A retrospective, nonrandomized study of the long-term outcome of biliary reconstructions after major BDIs. All injuries occurred in association with cholecystectomy.
RESULTS: Twenty-nine patients were referred with complete transection of the common (n = 16), right (n = 5), or right sectoral (n = 4) hepatic ducts or of >1 major duct (n = 4) between October 2002 and January 2007. Mean follow-up was 24 months, range 12-60 months. Original repairs were "immediate" in 14, "delayed" (within 24-72h) in 5, and "elective" (after >8 weeks) in 10, and strictures developed in 9, 5, and 1 of those HJs, respectively. The surgical outcomes were significantly better when the intervention took place electively (p = 0.003). Original HJ repairs were done by a hepatobiliary surgeon (n = 23) or by a general surgeon (n = 6): the outcome was significantly better for the former (p < 0.001).
CONCLUSIONS: The 51.7% incidence of strictures after BDI repair in this study was higher than reported in the literature, probably because of selection bias secondary to the referral pattern. The timing of repair and the surgeon's expertise are significant risk factors of failure.

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Year:  2008        PMID: 18493825     DOI: 10.1007/s11605-008-0538-3

Source DB:  PubMed          Journal:  J Gastrointest Surg        ISSN: 1091-255X            Impact factor:   3.452


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3.  Impaired quality of life 5 years after bile duct injury during laparoscopic cholecystectomy: a prospective analysis.

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4.  Recurrent biliary stricture. Patterns of recurrence and outcome of surgical therapy.

Authors:  C A Pellegrini; M J Thomas; L W Way
Journal:  Am J Surg       Date:  1984-01       Impact factor: 2.565

5.  Surgical management of bile duct injuries sustained during laparoscopic cholecystectomy: perioperative results in 200 patients.

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6.  Laparoscopic cholecystectomy-related bile duct injuries: a health and financial disaster.

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4.  Transition from a low: to a high-volume centre for bile duct repair: changes in technique and improved outcome.

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6.  Long-term effects and quality of life following definitive bile duct reconstruction.

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7.  Percutaneous transhepatic balloon dilation of biliary-enteric anastomotic strictures after surgical repair of iatrogenic bile duct injuries.

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Review 10.  Optimal timing for surgical reconstruction of bile duct injury: meta-analysis.

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