Literature DB >> 18491870

Thiamin diphosphate catalysis: enzymic and nonenzymic covalent intermediates.

Ronald Kluger1, Kai Tittmann.   

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Year:  2008        PMID: 18491870     DOI: 10.1021/cr068444m

Source DB:  PubMed          Journal:  Chem Rev        ISSN: 0009-2665            Impact factor:   60.622


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  49 in total

1.  Sub-ångström-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate.

Authors:  Stefan Lüdtke; Piotr Neumann; Karl M Erixon; Finian Leeper; Ronald Kluger; Ralf Ficner; Kai Tittmann
Journal:  Nat Chem       Date:  2013-08-18       Impact factor: 24.427

2.  Twisted Schiff base intermediates and substrate locale revise transaldolase mechanism.

Authors:  Anja Lehwess-Litzmann; Piotr Neumann; Christoph Parthier; Stefan Lüdtke; Ralph Golbik; Ralf Ficner; Kai Tittmann
Journal:  Nat Chem Biol       Date:  2011-08-21       Impact factor: 15.040

3.  Glyoxylate carboligase: a unique thiamin diphosphate-dependent enzyme that can cycle between the 4'-aminopyrimidinium and 1',4'-iminopyrimidine tautomeric forms in the absence of the conserved glutamate.

Authors:  Natalia Nemeria; Elad Binshtein; Hetalben Patel; Anand Balakrishnan; Ilan Vered; Boaz Shaanan; Ze'ev Barak; David Chipman; Frank Jordan
Journal:  Biochemistry       Date:  2012-09-25       Impact factor: 3.162

4.  Isotope effect, mechanism, and origin of catalysis in the decarboxylation of mandelylthiamin.

Authors:  Ollie M Gonzalez-James; Daniel A Singleton
Journal:  J Am Chem Soc       Date:  2010-05-26       Impact factor: 15.419

5.  Unexpected tautomeric equilibria of the carbanion-enamine intermediate in pyruvate oxidase highlight unrecognized chemical versatility of thiamin.

Authors:  Danilo Meyer; Piotr Neumann; Eline Koers; Hanno Sjuts; Stefan Lüdtke; George M Sheldrick; Ralf Ficner; Kai Tittmann
Journal:  Proc Natl Acad Sci U S A       Date:  2012-06-22       Impact factor: 11.205

6.  Crystal structures of phosphoketolase: thiamine diphosphate-dependent dehydration mechanism.

Authors:  Ryuichiro Suzuki; Takane Katayama; Byung-Jun Kim; Takayoshi Wakagi; Hirofumi Shoun; Hisashi Ashida; Kenji Yamamoto; Shinya Fushinobu
Journal:  J Biol Chem       Date:  2010-08-24       Impact factor: 5.157

Review 7.  Experimental observation of thiamin diphosphate-bound intermediates on enzymes and mechanistic information derived from these observations.

Authors:  Frank Jordan; Natalia S Nemeria
Journal:  Bioorg Chem       Date:  2005-04-01       Impact factor: 5.275

8.  Observation of thiamin-bound intermediates and microscopic rate constants for their interconversion on 1-deoxy-D-xylulose 5-phosphate synthase: 600-fold rate acceleration of pyruvate decarboxylation by D-glyceraldehyde-3-phosphate.

Authors:  Hetalben Patel; Natalia S Nemeria; Leighanne A Brammer; Caren L Freel Meyers; Frank Jordan
Journal:  J Am Chem Soc       Date:  2012-10-26       Impact factor: 15.419

9.  Artificial enzymes with thiazolium and imidazolium coenzyme mimics.

Authors:  Huanyu Zhao; Frank W Foss; Ronald Breslow
Journal:  J Am Chem Soc       Date:  2008-09-03       Impact factor: 15.419

10.  Structure and reactivity of Bacillus subtilis MenD catalyzing the first committed step in menaquinone biosynthesis.

Authors:  Alice Dawson; Minjiao Chen; Paul K Fyfe; Zhihong Guo; William N Hunter
Journal:  J Mol Biol       Date:  2010-06-18       Impact factor: 5.469

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