Literature DB >> 18490505

Postantibiotic effects and bactericidal activities of levofloxacin and gatifloxacin at concentrations simulating those of topical ophthalmic administration against fluoroquinolone-resistant and fluoroquinolone-sensitive methicillin-resistant Staphylococcus aureus strains.

Saichi Hoshi1, Ken Kikuchi, Takashi Sasaki, Chie Sotozono, Shigeru Kinoshita, Keiichi Hiramatsu.   

Abstract

The bactericidal activities and postantibiotic effects (PAEs) of levofloxacin and gatifloxacin at concentrations corresponding to those in antibiotic eye drops against methicillin-resistant Staphylococcus aureus strains were determined. Levofloxacin and gatifloxacin at concentrations simulating those in eye drops showed lower bactericidal activities and shorter PAEs against fluoroquinolone-resistant strains than against fluoroquinolone-sensitive strains.

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Year:  2008        PMID： 18490505      PMCID： PMC2493124          DOI： 10.1128/AAC.01466-07

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  30 in total

1.  In vitro activity of fluoroquinolones, vancomycin, and gentamicin against methicillin-resistant Staphylococcus aureus ocular isolates.

Authors:  Brett S Kotlus; Richard A Wymbs; Ernestine M Vellozzi; Ira J Udell
Journal:  Am J Ophthalmol       Date:  2006-11       Impact factor: 5.258

2.  Molecular characterization of 8-methoxyfluoroquinolone resistance in a clinical isolate of methicillin-resistant Staphylococcus aureus.

Authors:  Toshinobu Horii; Yasuhiro Suzuki; Akihiro Takeshita; Masato Maekawa
Journal:  Chemotherapy       Date:  2007-01-05       Impact factor: 2.544

3.  Mechanisms and frequency of resistance to gatifloxacin in comparison to AM-1121 and ciprofloxacin in Staphylococcus aureus.

Authors:  D Ince; D C Hooper
Journal:  Antimicrob Agents Chemother       Date:  2001-10       Impact factor: 5.191

4.  Endophthalmitis after uncomplicated cataract surgery with the use of fourth-generation fluoroquinolones: a retrospective observational case series.

Authors:  Majid Moshirfar; Vahid Feiz; Albert T Vitale; Jacob A Wegelin; Screenivasa Basavanthappa; Darcey H Wolsey
Journal:  Ophthalmology       Date:  2006-12-20       Impact factor: 12.079

5.  Emerging multiple mutations and high-level fluoroquinolone resistance in methicillin-resistant Staphylococcus aureus isolated from ocular infections.

Authors:  Hirotoshi Iihara; Takashi Suzuki; Yoshiaki Kawamura; Kiyofumi Ohkusu; Yasushi Inoue; Wei Zhang; Mohammad Monir Shah; Yoshihiro Katagiri; Yuichi Ohashi; Takayuki Ezaki
Journal:  Diagn Microbiol Infect Dis       Date:  2006-06-12       Impact factor: 2.803

6.  Ophthalmic manifestations of infections caused by the USA300 clone of community-associated methicillin-resistant Staphylococcus aureus.

Authors:  Tina Rutar; Henry F Chambers; J Brooks Crawford; Francoise Perdreau-Remington; Orin M Zwick; Michael Karr; Jennifer J Diehn; Kimberly P Cockerham
Journal:  Ophthalmology       Date:  2006-06-12       Impact factor: 12.079

7.  Shifting trends in bacterial keratitis in south Florida and emerging resistance to fluoroquinolones.

Authors:  G Alexandrakis; E C Alfonso; D Miller
Journal:  Ophthalmology       Date:  2000-08       Impact factor: 12.079

8.  Fluoroquinolone and fortified antibiotics for treating bacterial corneal ulcers.

Authors:  N Gangopadhyay; M Daniell; L Weih; H R Taylor
Journal:  Br J Ophthalmol       Date:  2000-04       Impact factor: 4.638

9.  Methicillin-resistant Staphylococcus aureus infectious keratitis following refractive surgery.

Authors:  Renée Solomon; Eric D Donnenfeld; Henry D Perry; Roy S Rubinfeld; Michael Ehrenhaus; John R Wittpenn; Kerry D Solomon; Edward E Manche; Majid Moshirfar; Dennis C Matzkin; Reza M Mozayeni; Robert K Maloney
Journal:  Am J Ophthalmol       Date:  2007-02-23       Impact factor: 5.258

10.  Increased incidence of corneal perforation after topical fluoroquinolone treatment for microbial keratitis.

Authors:  P L Mallari; D J McCarty; M Daniell; H Taylor
Journal:  Am J Ophthalmol       Date:  2001-01       Impact factor: 5.258
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  3 in total

Review 1.  Levofloxacin 0.5% ophthalmic solution: a review of its use in the treatment of external ocular infections and in intraocular surgery.

Authors:  Gillian M Keating
Journal:  Drugs       Date:  2009-06-18       Impact factor: 9.546

2.  Gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis: safety, efficacy and patient perspective.

Authors:  Clyde Schultz
Journal:  Ophthalmol Eye Dis       Date:  2012-07-11

3.  Antibacterial activity of a DNA topoisomerase I inhibitor versus fluoroquinolones in Streptococcus pneumoniae.

Authors:  Myriam V Valenzuela; Mirian Domenech; Patricia Mateos-Martínez; Fernando González-Camacho; Adela G de la Campa; Maria Teresa García
Journal:  PLoS One       Date:  2020-11-03       Impact factor: 3.240
  3 in total

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