Literature DB >> 18489657

Skeletal age of individuals with Down syndrome.

Mari Eli Leonelli de Moraes1, Jefferson Luis Oshiro Tanaka, Luis Cesar de Moraes, Edmundo Medici Filho, Julio Cezar de Melo Castilho.   

Abstract

The aim of this study was to assess the skeletal age of Brazilian individuals with Down syndrome (DS) using the method of Greulich and Pyle. Forty subjects with DS between the ages of 6 and 16 years were studied and compared to a control sample of children without DS. The statistical analysis showed that at the age of 7 years the skeletal age (SA) of the individuals with DS was delayed in relation to their chronological age (CA) (SA < CA). On the other hand, at the age of 15 years, their SA was advanced in relation to their CA (SA > CA). An evaluation of the results suggests that the period of adolescent development for individuals with DS was shorter. These individuals reach the completion of bone maturation earlier compared to individuals without DS.

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Year:  2008        PMID: 18489657     DOI: 10.1111/j.1754-4505.2008.00020.x

Source DB:  PubMed          Journal:  Spec Care Dentist        ISSN: 0275-1879


  9 in total

1.  Disruption of bone development and homeostasis by trisomy in Ts65Dn Down syndrome mice.

Authors:  Joshua D Blazek; Anna Gaddy; Rachel Meyer; Randall J Roper; Jiliang Li
Journal:  Bone       Date:  2010-09-24       Impact factor: 4.398

Review 2.  Skeletal dynamics of Down syndrome: A developing perspective.

Authors:  Jonathan M LaCombe; Randall J Roper
Journal:  Bone       Date:  2019-12-27       Impact factor: 4.398

Review 3.  Current Analysis of Skeletal Phenotypes in Down Syndrome.

Authors:  Jared R Thomas; Randall J Roper
Journal:  Curr Osteoporos Rep       Date:  2021-04-08       Impact factor: 5.163

4.  Growth charts for Brazilian children with Down syndrome: Birth to 20 years of age.

Authors:  Fabio Bertapelli; Stamatis Agiovlasitis; Maira Rossmann Machado; Raísa do Val Roso; Gil Guerra-Junior
Journal:  J Epidemiol       Date:  2017-03-18       Impact factor: 3.211

5.  Interaction of sexual dimorphism and gene dosage imbalance in skeletal deficits associated with Down syndrome.

Authors:  Jared R Thomas; Jonathan LaCombe; Rachel Long; Eva Lana-Elola; Sheona Watson-Scales; Joseph M Wallace; Elizabeth M C Fisher; Victor L J Tybulewicz; Randall J Roper
Journal:  Bone       Date:  2020-04-17       Impact factor: 4.398

6.  Skeletal Deficits in Male and Female down Syndrome Model Mice Arise Independent of Normalized Dyrk1a Expression in Osteoblasts.

Authors:  Jared R Thomas; Kourtney Sloan; Kelsey Cave; Joseph M Wallace; Randall J Roper
Journal:  Genes (Basel)       Date:  2021-10-28       Impact factor: 4.141

7.  Increased dosage and treatment time of Epigallocatechin-3-gallate (EGCG) negatively affects skeletal parameters in normal mice and Down syndrome mouse models.

Authors:  Raza Jamal; Jonathan LaCombe; Roshni Patel; Matthew Blackwell; Jared R Thomas; Kourtney Sloan; Joseph M Wallace; Randall J Roper
Journal:  PLoS One       Date:  2022-02-23       Impact factor: 3.752

8.  Ultrasonic bone age fractionates cognitive abilities in adolescence.

Authors:  Ilona Kovács; Kristóf Kovács; Patrícia Gerván; Katinka Utczás; Gyöngyi Oláh; Zsófia Tróznai; Andrea Berencsi; Hanna Szakács; Ferenc Gombos
Journal:  Sci Rep       Date:  2022-03-29       Impact factor: 4.379

9.  Green Tea Catechins Modulate Skeletal Development with Effects Dependent on Dose, Time, and Structure in a down Syndrome Mouse Model.

Authors:  Sergi Llambrich; Rubèn González-Colom; Jens Wouters; Jorge Roldán; Sara Salassa; Kaat Wouters; Vicky Van Bulck; James Sharpe; Zsuzsanna Callaerts-Vegh; Greetje Vande Velde; Neus Martínez-Abadías
Journal:  Nutrients       Date:  2022-10-07       Impact factor: 6.706

  9 in total

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