Literature DB >> 18488747

[Localization of adipose tissue: clinical implications].

Céline Leyvraz1, Chantal Verdumo, Vittorio Giusti.   

Abstract

The excessive accumulation of the adipose tissue is at the origin of the obesity. However its severity has no direct correlation with the comorbidities. These last ones are rather linked to the type of distribution of the fat than to its total quantity. The morphological and functional analysis of the adipose tissue reveals specific differences in its localization. The adipose tissue is thus a complex organ constituted by several cell types having various capacities of hypertrophy, hyperplasia and differentiation. While the first one is more predominant in the subcutaneous compartment, where the cell size is big, the others are more specific of the visceral adipocytes. Finally the severity of the obesity is linked to hypertrophy, while the comorbidities are associated with the capacity of proliferation and differentiation.

Entities:  

Mesh:

Year:  2008        PMID: 18488747

Source DB:  PubMed          Journal:  Rev Med Suisse        ISSN: 1660-9379


  2 in total

1.  SIRT1 transcription is decreased in visceral adipose tissue of morbidly obese patients with severe hepatic steatosis.

Authors:  Cíntia dos Santos Costa; Thais Ortiz Hammes; Francieli Rohden; Rogério Margis; Josiane Woutheres Bortolotto; Alexandre Vontobel Padoin; Cláudio Cora Mottin; Regina Maria Guaragna
Journal:  Obes Surg       Date:  2009-12-22       Impact factor: 4.129

2.  MicroRNA-125a-5p Mediates 3T3-L1 Preadipocyte Proliferation and Differentiation.

Authors:  Yan Xu; Jingjing Du; Peiwen Zhang; Xue Zhao; Qiang Li; Anan Jiang; Dongmei Jiang; Guoqing Tang; Yanzhi Jiang; Jinyong Wang; Xuewei Li; Shunhua Zhang; Li Zhu
Journal:  Molecules       Date:  2018-02-02       Impact factor: 4.411

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.