| Literature DB >> 18485829 |
Michela Mariottini1, Ilaria Corsi, Camilla Della Torre, Tancredi Caruso, Aldo Bianchini, Ilaria Nesi, Silvia Focardi.
Abstract
Polybrominated diphenyl ethers (PBDEs) and cytochrome P450 enzyme activities were investigated in European eels (Anguilla anguilla) collected from seven sites in a coastal lagoon in the north-western Mediterranean Sea, Orbetello lagoon (Italy). Twelve PBDE congeners were measured in muscle and two CYP1A enzyme activities, 7-ethoxyresorufin-O-deethylase (EROD) and benzo(a)pyrene monooxygenase (BP(a)PMO), were investigated in liver microsomal fraction in order to obtain insights into the health of the lagoon environment. PBDE muscle levels were low and the most abundant congeners were 2,2',4,4'-tetrabromodiphenylether (BDE-47), 2,2',4,4',5,5'-hexaBDE (BDE-153) and 2,2',4,5'-tetraBDE (BDE-49). EROD and B(a)PMO activities were also low and no differences were observed between eels from different sites. Multivariate analysis (PCA) did not indicate correlations between PBDEs and either P450 activities.Entities:
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Year: 2008 PMID： 18485829 DOI： 10.1016/j.cbpc.2008.03.011
Source DB: PubMed Journal: Comp Biochem Physiol C Toxicol Pharmacol ISSN： 1532-0456 Impact factor: 3.228