BACKGROUND: Cardiac autonomic nervous system (ANS) dysfunction in Huntington's disease (HD) might affect both the sympathetic and parasympathetic branch of the ANS. RESULTS AND CONCLUSIONS: The pattern of linear heart rate variability we found in mid stage HD patients points towards a predominately reduced cardiovagal modulation compared with healthy subjects, which might influence HD patients' susceptibility for cardiovascular complications such as syncopes and cardiac arrhythmias.
BACKGROUND:Cardiac autonomic nervous system (ANS) dysfunction in Huntington's disease (HD) might affect both the sympathetic and parasympathetic branch of the ANS. RESULTS AND CONCLUSIONS: The pattern of linear heart rate variability we found in mid stage HDpatients points towards a predominately reduced cardiovagal modulation compared with healthy subjects, which might influence HDpatients' susceptibility for cardiovascular complications such as syncopes and cardiac arrhythmias.
Authors: Takashi Kudo; Analyne Schroeder; Dawn H Loh; Dika Kuljis; Maria C Jordan; Kenneth P Roos; Christopher S Colwell Journal: Exp Neurol Date: 2010-12-22 Impact factor: 5.330
Authors: Benjamin Smarr; Tamara Cutler; Dawn H Loh; Takashi Kudo; Dika Kuljis; Lance Kriegsfeld; Cristina A Ghiani; Christopher S Colwell Journal: J Neurosci Res Date: 2019-07-29 Impact factor: 4.164
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Authors: Helen Kiriazis; Nicole L Jennings; Pamela Davern; Gavin Lambert; Yidan Su; Terence Pang; Xin Du; Luisa La Greca; Geoffrey A Head; Anthony J Hannan; Xiao-Jun Du Journal: J Physiol Date: 2012-08-13 Impact factor: 5.182
Authors: Guido Buonincontri; Nigel I Wood; Simon G Puttick; Alex O Ward; T Adrian Carpenter; Stephen J Sawiak; A Jennifer Morton Journal: J Huntingtons Dis Date: 2014