Literature DB >> 18484728

Copper-catalyzed alkyne-aryne and alkyne-alkene-aryne coupling reactions.

Chunsong Xie1, Leifang Liu, Yuhong Zhang, Peixin Xu.   

Abstract

The efficient copper-catalyzed two-component coupling reaction of alkynes with arynes and the three-component coupling reaction of alkynes with allylic chlorides and arynes have been developed. Copper acetylide was postulated as a transient intermediate for the initiation of the coupling reactions.

Entities:  

Year:  2008        PMID： 18484728     DOI： 10.1021/ol800651h

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  7 in total

1.  CuI -Mediated Bromoalkynylation and Hydroalkynylation Reactions of Unsymmetrical Benzynes: Complementary Modes of Addition.

Authors:  Xiao Xiao; Tao Wang; Feng Xu; Thomas R Hoye
Journal:  Angew Chem Int Ed Engl       Date:  2018-11-15       Impact factor: 15.336

2.  Transition-metal-free alkynylation of aryl chlorides.

Authors:  Thanh Truong; Olafs Daugulis
Journal:  Org Lett       Date:  2011-07-25       Impact factor: 6.005

3.  Enamide-benzyne-[2 + 2] cycloaddition: stereoselective tandem [2 + 2]-pericyclic ring-opening-intramolecular N-tethered [4 + 2] cycloadditions.

Authors:  John B Feltenberger; Ryuji Hayashi; Yu Tang; Eric S C Babiash; Richard P Hsung
Journal:  Org Lett       Date:  2009-08-20       Impact factor: 6.005

4.  Synthesis and application of a novel bis-1,2,3-triazole ligand containing a 2,2'-bipyrrolidine core.

Authors:  Stephen E Motika; Xiaodong Shi
Journal:  ARKIVOC       Date:  2018-01-28       Impact factor: 1.140

5.  Total syntheses of chelidonine and norchelidonine via an enamide-benzyne-[2 + 2] cycloaddition cascade.

Authors:  Zhi-Xiong Ma; John B Feltenberger; Richard P Hsung
Journal:  Org Lett       Date:  2012-05-10       Impact factor: 6.005

6.  Lipase-catalyzed kinetic resolution of aryltrimethylsilyl chiral alcohols.

Authors:  Dayvson J Palmeira; Juliana C Abreu; Leandro H Andrade
Journal:  Molecules       Date:  2011-11-23       Impact factor: 4.411

7.  Cu(I)-Catalyzed 1,2-Alkynyl-propargylation and -benzylation of Benzyne Derivatives.

Authors:  Qile Wang; Thomas R Hoye
Journal:  Org Lett       Date:  2021-06-28       Impact factor: 6.072
  7 in total

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