Literature DB >> 18483

Interaction of local anesthetics with the transport system of glucose in human erythrocytes.

L Lacko, B Wittke, I Lacko.   

Abstract

Local anesthetics inhibit the exhange transport of glucose in human erythroytes. All compounds tested showed a competitive inhibition except lidocaine and baycaine causing a non-competitive one. Moreover the transport system can bind two inhibitor molecules to one transport site as described for tetracaine and oxybuprocaine.

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Year:  1977        PMID： 18483     DOI： 10.1002/jcp.1040920214

Source DB:  PubMed          Journal:  J Cell Physiol        ISSN： 0021-9541            Impact factor:   6.384


  5 in total

1.  Different concentrations of local anaesthetics have different modes of action on human lymphocytes.

Authors:  G V Ramus; L Cesano; A Barbalonga
Journal:  Agents Actions       Date:  1983-06

2.  Local anesthetics, mepacrine, and propranolol are antagonists of calmodulin.

Authors:  M Volpi; R I Sha'afi; P M Epstein; D M Andrenyak; M B Feinstein
Journal:  Proc Natl Acad Sci U S A       Date:  1981-02       Impact factor: 11.205

3.  Effect of lidocaine on in vitro absorption of glucose in jejunal and ileal segments of the rat.

Authors:  G J Strugala; W Forth
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1984-06       Impact factor: 3.000

4.  Urea and ethylene glycol-facilitated transport systems in the human red cell membrane. Saturation, competition, and asymmetry.

Authors:  R R Mayrand; D G Levitt
Journal:  J Gen Physiol       Date:  1983-02       Impact factor: 4.086

5.  Local anesthetic-induced inhibition of collagen secretion in cultured cells under conditions where microtubules are not depolymerized by these agents.

Authors:  J H Eichhorn; B Peterkofsky
Journal:  J Cell Biol       Date:  1979-04       Impact factor: 10.539
  5 in total

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