Literature DB >> 18482693

Joining the army of proteasome inhibitors.

Alexei F Kisselev1.   

Abstract

An article in this issue of Chemistry & Biology (Hines et al., 2008) and a recent study in Nature (Groll et al., 2008) establish three natural products as novel proteasome inhibitors. These inhibitors, discovered in an unusual way, reveal a different mechanism of proteasome inhibition and suggest new therapeutic application of its inhibitors.

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Year:  2008        PMID: 18482693     DOI: 10.1016/j.chembiol.2008.04.010

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  14 in total

Review 1.  The ubiquitin/26S proteasome system in plant-pathogen interactions: a never-ending hide-and-seek game.

Authors:  Anne-Sophie Dielen; Saloua Badaoui; Thierry Candresse; Sylvie German-Retana
Journal:  Mol Plant Pathol       Date:  2010-03       Impact factor: 5.663

Review 2.  Culture-independent discovery of natural products from soil metagenomes.

Authors:  Micah Katz; Bradley M Hover; Sean F Brady
Journal:  J Ind Microbiol Biotechnol       Date:  2015-11-19       Impact factor: 3.346

3.  Syrbactin proteasome inhibitor TIR-199 overcomes bortezomib chemoresistance and inhibits multiple myeloma tumor growth in vivo.

Authors:  Marquicia R Pierce; Reeder M Robinson; Tannya R Ibarra-Rivera; Michael C Pirrung; Nathan G Dolloff; André S Bachmann
Journal:  Leuk Res       Date:  2019-11-12       Impact factor: 3.156

4.  Specific cell-permeable inhibitor of proteasome trypsin-like sites selectively sensitizes myeloma cells to bortezomib and carfilzomib.

Authors:  Anne C Mirabella; Alexandre A Pletnev; Sondra L Downey; Bogdan I Florea; Tamer B Shabaneh; Matthew Britton; Martijn Verdoes; Dmitri V Filippov; Herman S Overkleeft; Alexei F Kisselev
Journal:  Chem Biol       Date:  2011-05-27

5.  Fundamental reaction pathway and free energy profile for inhibition of proteasome by Epoxomicin.

Authors:  Donghui Wei; Beilei Lei; Mingsheng Tang; Chang-Guo Zhan
Journal:  J Am Chem Soc       Date:  2012-06-14       Impact factor: 15.419

6.  Fundamental reaction pathway and free energy profile of proteasome inhibition by syringolin A (SylA).

Authors:  Donghui Wei; Mingsheng Tang; Chang-Guo Zhan
Journal:  Org Biomol Chem       Date:  2015-06-28       Impact factor: 3.876

7.  Substituted quinolines as noncovalent proteasome inhibitors.

Authors:  Tanner J McDaniel; Theresa A Lansdell; Amila A Dissanayake; Lauren M Azevedo; Jacob Claes; Aaron L Odom; Jetze J Tepe
Journal:  Bioorg Med Chem       Date:  2016-04-02       Impact factor: 3.641

Review 8.  Multivalency-assisted control of intracellular signaling pathways: application for ubiquitin- dependent N-end rule pathway.

Authors:  Shashikanth M Sriram; Rajkumar Banerjee; Ravi S Kane; Yong Tae Kwon
Journal:  Chem Biol       Date:  2009-02-27

9.  Noncompetitive modulation of the proteasome by imidazoline scaffolds overcomes bortezomib resistance and delays MM tumor growth in vivo.

Authors:  Theresa A Lansdell; Michelle A Hurchla; Jingyu Xiang; Stacy Hovde; Katherine N Weilbaecher; R William Henry; Jetze J Tepe
Journal:  ACS Chem Biol       Date:  2012-12-11       Impact factor: 5.100

10.  Inhibition of the human proteasome by imidazoline scaffolds.

Authors:  Lauren M Azevedo; Theresa A Lansdell; Jacob R Ludwig; Robert A Mosey; Daljinder K Woloch; Dillon P Cogan; Gregory P Patten; Michael R Kuszpit; Jason S Fisk; Jetze J Tepe
Journal:  J Med Chem       Date:  2013-07-03       Impact factor: 7.446

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