BACKGROUND: Nurses' ability to rapidly detect decreases in cerebral perfusion pressure (CPP), which may contribute to secondary brain injury, may be limited by poor visibility of CPP displays. OBJECTIVE: To evaluate the impact of a highly visible CPP display on the functional outcome in individuals with cerebral aneurysms. METHODS:Patients with cerebral aneurysms (n = 100) who underwent continuous CPP monitoring were enrolled and randomized to beds with or without the additional CPP display. Six-month outcome was assessed. RESULTS:Functional outcome was not significantly different between control and intervention groups after controlling for initial neurologic condition (odds ratio .904, 95% confidence interval 0.317 to 2.573). However, greater time below CPP thresholds (55 to 70 mm Hg) was significantly associated with poorer outcome (P = .005 to .010). CONCLUSIONS: Although the enhanced CPP display was not associated with significantly better outcome, longer periods of CPP below set levels were associated with poorer outcome.
RCT Entities:
BACKGROUND: Nurses' ability to rapidly detect decreases in cerebral perfusion pressure (CPP), which may contribute to secondary brain injury, may be limited by poor visibility of CPP displays. OBJECTIVE: To evaluate the impact of a highly visible CPP display on the functional outcome in individuals with cerebral aneurysms. METHODS:Patients with cerebral aneurysms (n = 100) who underwent continuous CPP monitoring were enrolled and randomized to beds with or without the additional CPP display. Six-month outcome was assessed. RESULTS: Functional outcome was not significantly different between control and intervention groups after controlling for initial neurologic condition (odds ratio .904, 95% confidence interval 0.317 to 2.573). However, greater time below CPP thresholds (55 to 70 mm Hg) was significantly associated with poorer outcome (P = .005 to .010). CONCLUSIONS: Although the enhanced CPP display was not associated with significantly better outcome, longer periods of CPP below set levels were associated with poorer outcome.
Authors: M R Mayberg; H H Batjer; R Dacey; M Diringer; E C Haley; R C Heros; L L Sternau; J Torner; H P Adams; W Feinberg Journal: Stroke Date: 1994-11 Impact factor: 7.914
Authors: Pawan S Minhas; David K Menon; Piotr Smielewski; Marek Czosnyka; Peter J Kirkpatrick; John C Clark; John D Pickard Journal: Neurosurgery Date: 2003-05 Impact factor: 4.654
Authors: Rosalie G Waller; Melanie C Wright; Noa Segall; Paige Nesbitt; Thomas Reese; Damian Borbolla; Guilherme Del Fiol Journal: J Am Med Inform Assoc Date: 2019-05-01 Impact factor: 4.497
Authors: Melanie C Wright; Damian Borbolla; Rosalie G Waller; Guilherme Del Fiol; Thomas Reese; Paige Nesbitt; Noa Segall Journal: J Biomed Inform X Date: 2019-06-22