Literature DB >> 18482024

Tolperisone: a typical representative of a class of centrally acting muscle relaxants with less sedative side effects.

Stefan Quasthoff1, Claudia Möckel, Walter Zieglgänsberger, Wolfgang Schreibmayer.   

Abstract

Tolperisone, a piperidine derivative, is assigned to the group of centrally acting muscle relaxants and has been in clinical use now for decades. The review summarizes the known pharmacokinetics, pharmacodynamics, toxicology and side effects in humans and the clinical use of tolperisone. A future perspective for further exploration of this drug is given.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18482024      PMCID： PMC6494009          DOI： 10.1111/j.1527-3458.2008.00044.x

Source DB:  PubMed          Journal:  CNS Neurosci Ther        ISSN： 1755-5930            Impact factor:   5.243


  73 in total

1.  [Cavinton and mydocalm in combined therapy of anxiety disorders and tension headaches].

Authors:  V Solozhenkin
Journal:  Zh Nevrol Psikhiatr Im S S Korsakova       Date:  1999

2.  High performance thin layer chromatographic determination of tolperisone hydrochloride.

Authors:  S Liawruangrath; B Liawruangrath
Journal:  J Pharm Biomed Anal       Date:  1999-06       Impact factor: 3.935

3.  [Treatment of chronic arterial insufficiency of legs with midocalm in elderly].

Authors:  B S Briskin; M D Dibirov; Iu N Evseev; O S Novosel'tsev
Journal:  Khirurgiia (Mosk)       Date:  2000

4.  [Role of midocalm in combined treatment of neuropathic diabetic foot syndrome].

Authors:  B S Briskin; T I Sakunova; Ia I Iakobishvili
Journal:  Khirurgiia (Mosk)       Date:  2000

5.  [The use of midokalm in patients with multiple sclerosis].

Authors:  N Iu Lashch; G N Avakian
Journal:  Zh Nevrol Psikhiatr Im S S Korsakova       Date:  2000

6.  Separation of enantiomers on a chiral stationary phase based on ovoglycoprotein. VII. Comparison of chiral recognition ability of ovoglycoprotein from chicken and Japanese quail egg whites.

Authors:  J Haginaka; C Kagawa; H Matsunaga
Journal:  J Chromatogr A       Date:  1999-10-15       Impact factor: 4.759

7.  Chiral resolution of basic drugs by capillary electrophoresis with new glycosaminoglycans.

Authors:  T Tsukamoto; T Ushio; J Haginaka
Journal:  J Chromatogr A       Date:  1999-12-09       Impact factor: 4.759

8.  Method for recording spinal reflexes in mice: effects of thyrotropin-releasing hormone, DOI, tolperisone and baclofen on monosynaptic spinal reflex potentials.

Authors:  H Okada; M Honda; H Ono
Journal:  Jpn J Pharmacol       Date:  2001-05

9.  Intestinal first-pass metabolism of eperisone in the rat.

Authors:  K Mihara; M Matsumura; E Yoshioka; K Hanada; H Nakasa; S Ohmori; M Kitada; H Ogata
Journal:  Pharm Res       Date:  2001-08       Impact factor: 4.200

Review 10.  Systemic lidocaine for neuropathic pain relief.

Authors:  Jianren Mao; Lucy L Chen
Journal:  Pain       Date:  2000-07       Impact factor: 6.961
View more
  8 in total

1.  Influence of CYP2D6 and CYP2C19 genetic polymorphism on the pharmacokinetics of tolperisone in healthy volunteers.

Authors:  M Pawlowska; M Bogiel; J Duda; E Sieradzki
Journal:  Eur J Clin Pharmacol       Date:  2015-05-09       Impact factor: 2.953

2.  X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease.

Authors:  Sebastian Günther; Patrick Y A Reinke; Yaiza Fernández-García; Julia Lieske; Thomas J Lane; Helen M Ginn; Faisal H M Koua; Christiane Ehrt; Wiebke Ewert; Dominik Oberthuer; Oleksandr Yefanov; Susanne Meier; Kristina Lorenzen; Boris Krichel; Janine-Denise Kopicki; Luca Gelisio; Wolfgang Brehm; Ilona Dunkel; Brandon Seychell; Henry Gieseler; Brenna Norton-Baker; Beatriz Escudero-Pérez; Martin Domaracky; Sofiane Saouane; Alexandra Tolstikova; Thomas A White; Anna Hänle; Michael Groessler; Holger Fleckenstein; Fabian Trost; Marina Galchenkova; Yaroslav Gevorkov; Chufeng Li; Salah Awel; Ariana Peck; Miriam Barthelmess; Frank Schlünzen; P Lourdu Xavier; Nadine Werner; Hina Andaleeb; Najeeb Ullah; Sven Falke; Vasundara Srinivasan; Bruno Alves França; Martin Schwinzer; Hévila Brognaro; Cromarte Rogers; Diogo Melo; Joanna J Zaitseva-Doyle; Juraj Knoska; Gisel E Peña-Murillo; Aida Rahmani Mashhour; Vincent Hennicke; Pontus Fischer; Johanna Hakanpää; Jan Meyer; Philip Gribbon; Bernhard Ellinger; Maria Kuzikov; Markus Wolf; Andrea R Beccari; Gleb Bourenkov; David von Stetten; Guillaume Pompidor; Isabel Bento; Saravanan Panneerselvam; Ivars Karpics; Thomas R Schneider; Maria Marta Garcia-Alai; Stephan Niebling; Christian Günther; Christina Schmidt; Robin Schubert; Huijong Han; Juliane Boger; Diana C F Monteiro; Linlin Zhang; Xinyuanyuan Sun; Jonathan Pletzer-Zelgert; Jan Wollenhaupt; Christian G Feiler; Manfred S Weiss; Eike-Christian Schulz; Pedram Mehrabi; Katarina Karničar; Aleksandra Usenik; Jure Loboda; Henning Tidow; Ashwin Chari; Rolf Hilgenfeld; Charlotte Uetrecht; Russell Cox; Andrea Zaliani; Tobias Beck; Matthias Rarey; Stephan Günther; Dusan Turk; Winfried Hinrichs; Henry N Chapman; Arwen R Pearson; Christian Betzel; Alke Meents
Journal:  Science       Date:  2021-04-02       Impact factor: 47.728

3.  Clinical comparative study: efficacy and tolerability of tolperisone and thiocolchicoside in acute low back pain and spinal muscle spasticity.

Authors:  Rajeev Rao; Atul Panghate; Ajay Chandanwale; Indrajeet Sardar; Mriganka Ghosh; Modan Roy; Bireswar Banerjee; Ankur Goswami; Prakash P Kotwal
Journal:  Asian Spine J       Date:  2012-05-31

4.  Basic aspects of the pharmacodynamics of tolperisone, a widely applicable centrally acting muscle relaxant.

Authors:  Kornelia Tekes
Journal:  Open Med Chem J       Date:  2014-07-11

5.  The comparative study of clinical efficacy and safety of baclofen vs tolperisone in spasticity caused by spinal cord injury.

Authors:  Dejun Luo; Guoyong Wu; Yong Ji; Zhaoyao Zhang; Fayou He; Xiaping Mou; Qingmao Zhu; Bo Yang
Journal:  Saudi Pharm J       Date:  2017-05-07       Impact factor: 4.330

6.  Tolperisone for the Treatment of Acute Muscle Spasm of the Back: Results from the Dose-Ranging Phase 2 STAR Study (NCT03802565).

Authors:  Srinivas Nalamachu; Joseph Pergolizzi; Randall Kaye
Journal:  J Pain Res       Date:  2020-11-23       Impact factor: 3.133

7.  Risk factors of anaphylaxis in Korea: Identifying drug-induced anaphylaxis culprits using big data.

Authors:  Kyung-Min Ahn; Byung-Keun Kim; Min-Suk Yang
Journal:  Medicine (Baltimore)       Date:  2022-09-02       Impact factor: 1.817

8.  Antispasmodic Effect of Asperidine B, a Pyrrolidine Derivative, through Inhibition of L-Type Ca2+ Channel in Rat Ileal Smooth Muscle.

Authors:  Acharaporn Duangjai; Vatcharin Rukachaisirikul; Yaowapa Sukpondma; Chutima Srimaroeng; Chatchai Muanprasat
Journal:  Molecules       Date:  2021-09-09       Impact factor: 4.411
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.