| Literature DB >> 18481024 |
Leon Azefack Tapondjou1, Kemvoufo Beaudelaire Ponou, Remy Bertrand Teponno, Marius Mbiantcha, Jules Désiré Djoukeng, Télesphore Benoit Nguelefack, Pierre Watcho, Aurelio Gomez Cadenas, Hee-Juhn Park.
Abstract
A new steroidal saponin, mannioside A (1), was isolated from the stem bark of Dracaena mannii, together with the known pennogenin (2), pennogenin-3-O-beta-D-glucopyranoside (3) and pennogenin-3-O-alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranosyl-(1-->3)]-beta-D-glucopyranoside (4). Their structures were determined using 1D-and 2D-NMR spectroscopy and mass spectrometry. Compounds 1 and 3 significantly inhibited carrageenan-induced paw edema in the rat; compound 4 was moderately active whereas 2 showed very weak activity.Entities:
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Year: 2008 PMID： 18481024 DOI： 10.1007/s12272-001-1208-3
Source DB: PubMed Journal: Arch Pharm Res ISSN： 0253-6269 Impact factor: 4.946