Literature DB >> 18480921

Itch intensity evaluated in the German Atopic Dermatitis Intervention Study (GADIS): correlations with quality of life, coping behaviour and SCORAD severity in 823 children.

Elke Weisshaar1, Thomas L Diepgen, Thomas Bruckner, Manigé Fartasch, Jörg Kupfer, Thomas Lob-Corzilius, Johannes Ring, Sibylle Scheewe, Reginald Scheidt, Gerhard Schmid-Ott, Christina Schnopp, Doris Staab, Rüdiger Szcepanski, Thomas Werfel, Marita Wittenmeier, Ulrich Wahn, Uwe Gieler.   

Abstract

The German Atopic Dermatitis Intervention Study (GADIS), which includes 823 children and adolescents, showed that age-related educational programmes are effective in the long-term management of atopic dermatitis. We investigated whether the itch severity obtained in the scoring of atopic dermatitis (SCORAD) correlates with quality of life and coping behaviour in children and parents. There were significant but low correlations between the severity of atopic dermatitis and the itch intensity. Itch and sleeplessness were significantly correlated. Significant correlations of itch with the coping behaviour and quality of life in parents of children with atopic dermatitis were measured. The coping and itching behaviour of children (8-12 years) and adolescents (13-18 years) had higher significant correlations with the itch compared with the parents' answers. Quality of life in children (8-12 years) and adolescents (13-18 years) showed a significant negative correlation with itch intensity. Quality of life, itch intensity and coping strategies should be considered when treating patients with atopic dermatitis.

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Year:  2008        PMID: 18480921     DOI: 10.2340/00015555-0432

Source DB:  PubMed          Journal:  Acta Derm Venereol        ISSN: 0001-5555            Impact factor:   4.437


  14 in total

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Review 4.  Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis.

Authors:  Lawrence F Eichenfield; Wynnis L Tom; Sarah L Chamlin; Steven R Feldman; Jon M Hanifin; Eric L Simpson; Timothy G Berger; James N Bergman; David E Cohen; Kevin D Cooper; Kelly M Cordoro; Dawn M Davis; Alfons Krol; David J Margolis; Amy S Paller; Kathryn Schwarzenberger; Robert A Silverman; Hywel C Williams; Craig A Elmets; Julie Block; Christopher G Harrod; Wendy Smith Begolka; Robert Sidbury
Journal:  J Am Acad Dermatol       Date:  2013-11-27       Impact factor: 11.527

5.  [Somatoform pruritus: a psychosomatic disease model].

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Authors:  Patrick M Brunner; Donald Y M Leung; Emma Guttman-Yassky
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7.  Systemic Tofacitinib Concentrations in Adult Patients With Atopic Dermatitis Treated With 2% Tofacitinib Ointment and Application to Pediatric Study Planning.

Authors:  Vivek S Purohit; William C Ports; Cunshan Wang; Steve Riley
Journal:  J Clin Pharmacol       Date:  2018-12-17       Impact factor: 3.126

Review 8.  Comprehensive Approach: Current Status on Patient Education in Atopic Dermatitis and Other Allergic Diseases.

Authors:  Stephan Traidl; Claudia Lang; Peter Schmid-Grendelmeier; Thomas Werfel; Annice Heratizadeh
Journal:  Handb Exp Pharmacol       Date:  2022

Review 9.  Counting the Burden: Atopic Dermatitis and Health-related Quality of Life.

Authors:  Faraz Ali; Jui Vyas; Andrew Y Finlay
Journal:  Acta Derm Venereol       Date:  2020-06-09       Impact factor: 3.875

10.  Differences in Psychometric Properties of Clinician- and Patient-Reported Outcome Measures for Atopic Dermatitis by Race and Skin Tone: A Systematic Review.

Authors:  Trisha Kaundinya; Uros Rakita; Armaan Guraya; Donna Maria Abboud; Emily Croce; Jacob P Thyssen; Andrew Alexis; Jonathan I Silverberg
Journal:  J Invest Dermatol       Date:  2021-08-02       Impact factor: 8.551

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