Yann De Bast1, Laurent Dahin. 1. Vascular Surgery department, Saint Anne Saint Remi Clinic, Brussels, Belgium. ydebast@hotmail.com
Abstract
BACKGROUND: The May-Thurner syndrome is a deep venous thrombosis of the left iliofemoral vein due to a compression by the right primitive iliac artery. Some authors suggested that this syndrome could be associated with genetics factors predisposing to thrombophilia. OBJECTIVES: The aim of this article is to assess if the May-Thurner syndrome could be associated with inherited thombophilia particularly the factor V mutation. PATIENTS/ METHODS: We exposed three cases of May-Thurner syndrome, all were positive for the presence of factor V Leiden. CONCLUSION: Some olds syndromes can be revisited and explained by molecular research. In this case, the May-Thurner syndrome could be associated with inherited thrombophilia. This finding could explain the pathology but also open new treatments or guidelines for the management this kind of pathology.
BACKGROUND: The May-Thurner syndrome is a deep venous thrombosis of the left iliofemoral vein due to a compression by the right primitive iliac artery. Some authors suggested that this syndrome could be associated with genetics factors predisposing to thrombophilia. OBJECTIVES: The aim of this article is to assess if the May-Thurner syndrome could be associated with inherited thombophilia particularly the factor V mutation. PATIENTS/ METHODS: We exposed three cases of May-Thurner syndrome, all were positive for the presence of factor V Leiden. CONCLUSION: Some olds syndromes can be revisited and explained by molecular research. In this case, the May-Thurner syndrome could be associated with inherited thrombophilia. This finding could explain the pathology but also open new treatments or guidelines for the management this kind of pathology.