Literature DB >> 18479242

Intralesional injection of platelet-rich plasma followed by controlled exercise for treatment of midbody suspensory ligament desmitis in Standardbred racehorses.

Martin Waselau1, W Wesley Sutter, Ronald L Genovese, Alicia L Bertone.   

Abstract

OBJECTIVE: To determine outcome of Standardbred racehorses with moderate to severe midbody suspensory ligament desmitis (MSD) treated by means of ultrasound-guided intralesional injection of a single dose of platelet-rich plasma (PRP) followed by a program of gradually increased exercise.
DESIGN: Nonrandomized clinical trial. ANIMALS: 9 Standardbred racehorses. PROCEDURES: Following injection of PRP, horses were allowed a controlled, gradual return to exercise. Race records for the year prior to injury and for 3 consecutive years after horses returned to racing were reviewed. For comparison purposes, race records of 9 Standardbred racehorses with no history of MSD racing at the same time were also reviewed.
RESULTS: All 9 horses with MSD returned to racing after treatment; median time to return to racing was 32 weeks. All 9 horses raced at least once during the first and second years after returning to racing, but only 5 raced during the third year. When number of starts, total earnings, and earnings per start were compared between case and comparison horses, the only significant differences were number of starts during the third year after case horses returned to racing and earnings per start during the first year after case horses returned to racing, with values being significantly lower for case horses than for comparison horses. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggested that horses with moderate to severe MSD treated by means of intralesional injection of a single dose of PRP followed by a program of gradually increased exercise had an excellent prognosis for returning to racing.

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Year:  2008        PMID: 18479242     DOI: 10.2460/javma.232.10.1515

Source DB:  PubMed          Journal:  J Am Vet Med Assoc        ISSN: 0003-1488            Impact factor:   1.936


  25 in total

1.  An In Vitro Investigation of Platelet-Rich Plasma-Gel as a Cell and Growth Factor Delivery Vehicle for Tissue Engineering.

Authors:  Jagoda M Jalowiec; Matteo D'Este; Jennifer Jane Bara; Jessica Denom; Ursula Menzel; Mauro Alini; Sophie Verrier; Marietta Herrmann
Journal:  Tissue Eng Part C Methods       Date:  2015-12-01       Impact factor: 3.056

2.  Short- and long-term effects of platelet-rich plasma upon healthy equine joints: Clinical and laboratory aspects.

Authors:  Ana Paula L Moraes; Juliana J Moreira; Patrícia M Brossi; Thaís S L Machado; Yara M Michelacci; Raquel Y A Baccarin
Journal:  Can Vet J       Date:  2015-08       Impact factor: 1.008

3.  Using Short Term of High Power Laser Therapy in Horse's Tendon Injuries.

Authors:  S E Jaafar; A A H Al-Bayti; S I Abdullah
Journal:  Arch Razi Inst       Date:  2021-11-30

Review 4.  Tendon regeneration in human and equine athletes: Ubi Sumus-Quo Vadimus (where are we and where are we going to)?

Authors:  Jan H Spaas; Deborah J Guest; Gerlinde R Van de Walle
Journal:  Sports Med       Date:  2012-10-01       Impact factor: 11.136

5.  Simple tube centrifugation for processing platelet-rich plasma in the horse.

Authors:  Robin L Fontenot; Carolyn A Sink; Stephen R Werre; Nicole M Weinstein; Linda A Dahlgren
Journal:  Can Vet J       Date:  2012-12       Impact factor: 1.008

Review 6.  Platelet-rich plasma in orthopedic therapy: a comparative systematic review of clinical and experimental data in equine and human musculoskeletal lesions.

Authors:  Patrícia M Brossi; Juliana J Moreira; Thaís S L Machado; Raquel Y A Baccarin
Journal:  BMC Vet Res       Date:  2015-04-22       Impact factor: 2.741

7.  Effect of platelet-rich plasma on chondrogenic differentiation in three-dimensional culture.

Authors:  Steven Elder; John Thomason
Journal:  Open Orthop J       Date:  2014-04-04

8.  Comparison of the effect of calcium gluconate and batroxobin on the release of transforming growth factor beta 1 in canine platelet concentrates.

Authors:  Raul F Silva; Jorge U Carmona; Cleuza M F Rezende
Journal:  BMC Vet Res       Date:  2012-07-25       Impact factor: 2.741

9.  Evaluation of the effect of calcium gluconate and bovine thrombin on the temporal release of transforming growth factor beta 1 and platelet-derived growth factor isoform BB from feline platelet concentrates.

Authors:  Raul F Silva; María E Alvarez; Diana L Ríos; Catalina López; Jorge U Carmona; Cleuza Mf Rezende
Journal:  BMC Vet Res       Date:  2012-11-06       Impact factor: 2.741

10.  Effects of the breed, sex and age on cellular content and growth factor release from equine pure-platelet rich plasma and pure-platelet rich gel.

Authors:  Carlos E Giraldo; Catalina López; María E Álvarez; Ismael J Samudio; Marta Prades; Jorge U Carmona
Journal:  BMC Vet Res       Date:  2013-02-12       Impact factor: 2.741

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