Hong-Sheng Lin1, Dao-Rui Li. 1. Department of Medical Oncology, Guanganmen Hospital, China Academy of Chinese Traditional Medicine, Beijing 100053, China.
Abstract
OBJECTIVE: To investigate the effect of Shenqi-fuzheng injection combined with chemotherapy on the quality of life in lung cancer patient. METHODS:232 pathologically confirmed nonsmall cell lung cancer patients were enrolled into this multi-center randomized trial. Of these 232 patients, 116 cases were treated with chemotherapy alone (chemotherapy group), another 116 withchemotherapy combined with Shenqi-fuzheng injection produced by Lizhu Company (Shenqi-fuzheng group). Life quality of these patients were evaluated using the QOL scale of European Organization for Research on Treatment of Cancer (QLQ-C30) and the functional living index-cancer. RESULTS: Compared with chemotherapy group, Life quality and symptoms were improved in the Shenqi-fuzheng group, which including lassitude, deficient in breath, pain, fullness in chest and hypochondrium, excessive phlegm, cough, complexion whiteness. Response rate to chemotherapy was also improved. No AE and SAE were observed in the Shenqi-fuzheng group. CONCLUSION:Shenqi-fuzheng injection combined with chemotherapy is safe and effective in the treatment for non-small cell lung cancer.
RCT Entities:
OBJECTIVE: To investigate the effect of Shenqi-fuzheng injection combined with chemotherapy on the quality of life in lung cancerpatient. METHODS: 232 pathologically confirmed nonsmall cell lung cancerpatients were enrolled into this multi-center randomized trial. Of these 232 patients, 116 cases were treated with chemotherapy alone (chemotherapy group), another 116 with chemotherapy combined with Shenqi-fuzheng injection produced by Lizhu Company (Shenqi-fuzheng group). Life quality of these patients were evaluated using the QOL scale of European Organization for Research on Treatment of Cancer (QLQ-C30) and the functional living index-cancer. RESULTS: Compared with chemotherapy group, Life quality and symptoms were improved in the Shenqi-fuzheng group, which including lassitude, deficient in breath, pain, fullness in chest and hypochondrium, excessive phlegm, cough, complexion whiteness. Response rate to chemotherapy was also improved. No AE and SAE were observed in the Shenqi-fuzheng group. CONCLUSION: Shenqi-fuzheng injection combined with chemotherapy is safe and effective in the treatment for non-small cell lung cancer.
Authors: Libin Jia; Hongsheng Lin; Joost Oppenheim; O M Zack Howard; Jie Li; Huiting Fan; Zhizheng Zhao; William Farrar; Ying Zhang; Nancy Colburn; Matthew R Young; Weidong Li; David Newman; Barry R O'Keefe; John Beutler; Jikai Liu; Xiaojiang Hao; Xiaosheng Yang; Tengfei Ji; Jeffrey D White Journal: J Natl Cancer Inst Monogr Date: 2017-11-01
Authors: Yang Yang; Wang Ting; Liu Xiao; Fu Shufei; Tan Wangxiao; Wang Xiaoying; Gao Xiumei; Zhang Boli Journal: Evid Based Complement Alternat Med Date: 2017-01-05 Impact factor: 2.629