Literature DB >> 18478708

Highly enantioselective synthesis of isoxazoline N-oxides.

Chun-Yin Zhu1, Xian-Ming Deng, Xiu-Li Sun, Jun-Cheng Zheng, Yong Tang.   

Abstract

The reaction of cinchonidine (cinchonine)-derived ammonium salts with nitroolefins in the presence of Cs2CO3 to afford optically active isoxazoline N-oxides with excellent ee and high de values has been developed.

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Year:  2008        PMID： 18478708     DOI： 10.1039/b716468h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

1.  Identification of the best-suited leaving group for the diastereoselective synthesis of glycidic amides from stabilised ammonium ylides and aldehydes.

Authors:  Richard Herchl; Martin Stiftinger; Mario Waser
Journal:  Org Biomol Chem       Date:  2011-08-11       Impact factor: 3.876

2.  The Cyclic Nitronate Route to Pharmaceutical Molecules: Synthesis of GSK's Potent PDE4 Inhibitor as a Case Study.

Authors:  Evgeny V Pospelov; Ivan S Golovanov; Sema L Ioffe; Alexey Yu Sukhorukov
Journal:  Molecules       Date:  2020-08-08       Impact factor: 4.411

3.  Ammonium ylides for the diastereoselective synthesis of glycidic amides.

Authors:  Mario Waser; Richard Herchl; Norbert Müller
Journal:  Chem Commun (Camb)       Date:  2010-12-21       Impact factor: 6.222

4.  Comparison of Substituting Ability of Nitronate versus Enolate for Direct Substitution of a Nitro Group.

Authors:  Yusuke Mukaijo; Soichi Yokoyama; Nagatoshi Nishiwaki
Journal:  Molecules       Date:  2020-04-28       Impact factor: 4.411

5.  Ammonium Ylide Mediated Cyclization Reactions.

Authors:  Lukas Roiser; Katharina Zielke; Mario Waser
Journal:  Asian J Org Chem       Date:  2018-03-25       Impact factor: 3.319

6.  Formal (4+1)-Cyclization of Ammonium Ylides with Vinylogous para-Quinone Methides.

Authors:  Lukas Roiser; Katharina Zielke; Mario Waser
Journal:  Synthesis (Stuttg)       Date:  2018-09-05       Impact factor: 3.157
  6 in total

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