Literature DB >> 18478466

[Clinicopathological analysis of esophageal carcinosarcoma:a report of 22 cases].

Zhen Yu1, Bang-Chang Cheng, Sheng Chang, Jie Huang, Zhi-Fu Mao, Gan-Jun Kang, Hui-Qing Lin, Yong-Guang Xiao.   

Abstract

OBJECTIVE: To evaluate the clinicopathological characteristics and surgical treatment of esophageal carcinosarcoma.
METHODS: The patients with esophageal carcinosarcoma were divided into two types according to barium swallow: intraluminal carcinosarcoma (n=20) and fungating carcinosarcoma (n=2). Only one esophageal carcinosarcoma case was diagnosed by esophagoscopic biopsy preoperatively. Twenty patients underwent left thoracic approach esophagectomy and esophagogastrostomy above aortic arch, and two patients underwent esophagectomy and esophagogastrostomy below aortic arch.
RESULTS: All the cases survived during operation and had no severe complication. Post-operative biopsy revealed that 21 cases had definite boundary between the carcinoma and the sarcoma. Only one case showed the invasion of carcinomatous tissues into sarcomatous tissues and mixed growth. Four cases had lymph node metastases (18.2%). The 1-, 3- and 5-year survival rates were 90.9% (20/22), 77.3% (17/22) and 68.2% (15/22) respectively.
CONCLUSIONS: Esophageal carcinosarcoma is a rare malignant tumor with little invasiveness, low lymph node metastasis, early clinical symptom occurrence, low preoperative accurate diagnostic rate and good prognosis. Surgical resection is the main treatment for esophageal carcinosarcoma.

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Year:  2008        PMID: 18478466

Source DB:  PubMed          Journal:  Zhonghua Wei Chang Wai Ke Za Zhi        ISSN: 1671-0274


  2 in total

1.  Prognosis and prognostic factors of esophageal spindle cell carcinoma treated by esophagectomy: a retrospective single-institution analysis.

Authors:  Masashi Hashimoto; Hidehiko Kitagami; Hiroki Niwa; Tomohiro Kikkawa; Tomoyuki Ohuchi; Toshinao Takenouchi; Masao Hosokawa
Journal:  Esophagus       Date:  2019-04-01       Impact factor: 4.230

Review 2.  Esophageal Carcinosarcoma: Analysis of Clinical Features and Prognosis of 24 Cases and a Literature Review.

Authors:  Shusen Chen; Yu Shi; Zhengjing Lu; Mingwei Wang; Longfei Cong; Baixia Yang; Xudong Chen; Jing Cai; Xi Yang
Journal:  Cancer Control       Date:  2021 Jan-Dec       Impact factor: 3.302

  2 in total

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