Literature DB >> 18477488

Reproductive history, sexual behavior and use of contraception in women with epilepsy.

Anne R Davis1, Alison M Pack, Jordana Kritzer, Ava Yoon, Adela Camus.   

Abstract

BACKGROUND: Women with epilepsy experience more pregnancy-related risks than do their healthy peers. Guidelines recommend highly effective contraception. However, their contraceptive practices remain unknown. STUDY
DESIGN: We conducted a cross-sectional questionnaire study among reproductive-age women (18-44 years) with epilepsy presenting for routine, outpatient visits to an urban, academic medical center. Our questionnaire, in English or Spanish, included demographic characteristics, reproductive history, antiepileptic drug use, sexual behavior and contraception.
RESULTS: Participants had a mean age of 32 years (S.D.=8), 32% spoke Spanish and described themselves as Hispanic. Participants reported a wide range of educational attainment, insurance payor and income. About half of the participants reported at least one pregnancy, and 50% of the 181 pregnancies reported were unplanned. Among the 53% who reported intercourse in the last month, 74% used contraception, 15% were pregnant, 5% did not want to use contraception, 3% sought pregnancy and 3% had hysterectomy. Of those using contraception, 53% used highly effective methods (sterilization, intrauterine device, hormonal pill, patch and injection), and 47% used less effective methods (condom, withdrawal, rhythm and spermicide). Among the 21 participants using hormonal methods, six concomitantly took enzyme-inducing antiepileptic drugs potentially increasing susceptibility to pregnancy. DISCUSSION: In this sample of women with epilepsy about half reported prior pregnancies; 50% were unplanned. Of those using contraception, only 53% used a highly effective method. Future studies should determine generalizability of these findings and explore reasons for inadequate family planning in women with epilepsy.

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Year:  2008        PMID: 18477488     DOI: 10.1016/j.contraception.2008.02.002

Source DB:  PubMed          Journal:  Contraception        ISSN: 0010-7824            Impact factor:   3.375


  18 in total

1.  Too Complicated or So Simple: AED Type and AED Dose Matter for Pregnancy.

Authors:  Page B Pennell
Journal:  Epilepsy Curr       Date:  2012-03       Impact factor: 7.500

2.  Contraceptive Methods, Seizures, and Antiepileptic Drugs: More Questions Than Answers.

Authors:  Alison M Pack
Journal:  Epilepsy Curr       Date:  2017 Jan-Feb       Impact factor: 7.500

3.  Carbamazepine coadministration with an oral contraceptive: effects on steroid pharmacokinetics, ovulation, and bleeding.

Authors:  Anne R Davis; Carolyn L Westhoff; Frank Z Stanczyk
Journal:  Epilepsia       Date:  2011-01-04       Impact factor: 5.864

4.  Women's Preferred Sources for Primary and Mental Health Care: Implications for Reproductive Health Providers.

Authors:  Kelli Stidham Hall; Lisa H Harris; Vanessa K Dalton
Journal:  Womens Health Issues       Date:  2016-11-04

Review 5.  Contraceptive Care in the Veterans Health Administration.

Authors:  Emmanuelle B Yecies; Colleen P Judge-Golden; Lisa Callegari; Sonya Borrero
Journal:  Semin Reprod Med       Date:  2019-06-11       Impact factor: 1.303

6.  Stressful Life Events Around the Time of Unplanned Pregnancy and Women's Health: Exploratory Findings from a National Sample.

Authors:  Kelli Stidham Hall; Vanessa K Dalton; Melissa Zochowski; Timothy R B Johnson; Lisa H Harris
Journal:  Matern Child Health J       Date:  2017-06

7.  An educational intervention on drug interactions and contraceptive options for epilepsy patients: a pilot randomized controlled trial.

Authors:  Sheila K Mody; Carolyn Haunschild; John Paul Farala; Gordon Honerkamp-Smith; Vivian Hur; Leena Kansal
Journal:  Contraception       Date:  2015-07-18       Impact factor: 3.375

Review 8.  An Update on Maternal Use of Antiepileptic Medications in Pregnancy and Neurodevelopment Outcomes.

Authors:  Elizabeth E Gerard; Kimford J Meador
Journal:  J Pediatr Genet       Date:  2015-06

Review 9.  Hormonal aspects of epilepsy.

Authors:  Page B Pennell
Journal:  Neurol Clin       Date:  2009-11       Impact factor: 3.806

10.  Contraceptive Counseling and Use among Women with Poorer Health.

Authors:  Jessica K Lee; Sara M Parisi; Eleanor Bimla Schwarz
Journal:  J Womens Health Issues Care       Date:  2013
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