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Literature DB >> 18476126

Famciclovir (FAMVIR).

Abstract

Famciclovir is an antiviral with efficacy and safety comparable to aciclovir, but famciclovir's more favorable pharmacokinetic profile enables a less frequent dosing regimen. Future trials will likely determine famciclovir's role in the suppression of HBV.

Entities: Chemical

Year: 1997 PMID： 18476126 PMCID： PMC2364535 DOI： 10.1155/S1064744997000033

Source DB: PubMed Journal: Infect Dis Obstet Gynecol ISSN： 1064-7449

12 in total

1. Selection of an oral prodrug (BRL 42810; famciclovir) for the antiherpesvirus agent BRL 39123 [9-(4-hydroxy-3-hydroxymethylbut-l-yl)guanine; penciclovir].

Authors: R A Vere Hodge; D Sutton; M R Boyd; M R Harnden; R L Jarvest
Journal: Antimicrob Agents Chemother Date: 1989-10 Impact factor: 5.191

2. Patient-initiated, twice-daily oral famciclovir for early recurrent genital herpes. A randomized, double-blind multicenter trial. Canadian Famciclovir Study Group.

Authors: S L Sacks; F Y Aoki; F Diaz-Mitoma; J Sellors; S D Shafran
Journal: JAMA Date: 1996-07-03 Impact factor: 56.272

3. In vitro antiviral activity of penciclovir, a novel purine nucleoside, against duck hepatitis B virus.

Authors: T Shaw; P Amor; G Civitico; M Boyd; S Locarnini
Journal: Antimicrob Agents Chemother Date: 1994-04 Impact factor: 5.191

4. Pharmacokinetics of the acyclovir pro-drug valaciclovir after escalating single- and multiple-dose administration to normal volunteers.

Authors: S Weller; M R Blum; M Doucette; T Burnette; D M Cederberg; P de Miranda; M L Smiley
Journal: Clin Pharmacol Ther Date: 1993-12 Impact factor: 6.875

10. Oral famciclovir against duck hepatitis B virus replication in hepatic and nonhepatic tissues of ducklings infected in ovo.

Authors: K N Tsiquaye; M J Slomka; M Maung
Journal: J Med Virol Date: 1994-03 Impact factor: 2.327

1 in total

1. Novel drug delivery approaches on antiviral and antiretroviral agents.

Authors: Pooja Sharma; Anuj Chawla; Sandeep Arora; Pravin Pawar
Journal: J Adv Pharm Technol Res Date: 2012-07

1 in total

Famciclovir (FAMVIR).

1. Selection of an oral prodrug (BRL 42810; famciclovir) for the antiherpesvirus agent BRL 39123 [9-(4-hydroxy-3-hydroxymethylbut-l-yl)guanine; penciclovir].

2. Patient-initiated, twice-daily oral famciclovir for early recurrent genital herpes. A randomized, double-blind multicenter trial. Canadian Famciclovir Study Group.

3. In vitro antiviral activity of penciclovir, a novel purine nucleoside, against duck hepatitis B virus.

4. Pharmacokinetics of the acyclovir pro-drug valaciclovir after escalating single- and multiple-dose administration to normal volunteers.

5. Pharmacokinetics of famciclovir in subjects with varying degrees of renal impairment.

6. Prostaglandin E plus famciclovir--a new concept for the treatment of severe hepatitis B after liver transplantation.

Review 7. Famciclovir. A review of its pharmacological properties and therapeutic efficacy in herpesvirus infections.

8. Safety of famciclovir in patients with herpes zoster and genital herpes.

Review 9. Famciclovir: review of clinical efficacy and safety.

10. Oral famciclovir against duck hepatitis B virus replication in hepatic and nonhepatic tissues of ducklings infected in ovo.

1. Novel drug delivery approaches on antiviral and antiretroviral agents.