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Literature DB >> 18475509

Phospholipid derived mediators and glomerulonephritis.

Abstract

The contributions made by the various eicosanoids, PAF, the HETES and the lipoxins to the pathophysiology of glomerulonephritis is reviewed. A case can be made for clinical trials of PAF, leukotriene and thromboxane antagonists. Combined thromboxane synthetase and thromboxane receptor antagonism would seem to be the more efficacious approach for the various disease entities.

Entities: Chemical Disease

Year: 1993 PMID： 18475509 PMCID： PMC2365393 DOI： 10.1155/S0962935193000134

Source DB: PubMed Journal: Mediators Inflamm ISSN： 0962-9351 Impact factor: 4.711

44 in total

1. Lipocortin: what is it and what does it mean?

Authors: R J Flower
Journal: Br J Rheumatol Date: 1992-08

Review 2. TGF-beta: regulation of extracellular matrix.

Authors: A B Roberts; B K McCune; M B Sporn
Journal: Kidney Int Date: 1992-03 Impact factor: 10.612

3. Thromboxane mediates glomerular haemodynamics in a model of chronic glomerular disease.

Authors: F Thaiss; M J Mihatsch; W Schoeppe; R A Stahl
Journal: Eur J Clin Invest Date: 1992-03 Impact factor: 4.686

4. Relationship between hepatic lipid peroxidation and fibrogenesis in carbon tetrachloride-treated rats: effect of zinc administration.

Authors: J Camps; T Bargallo; A Gimenez; S Alie; J Caballeria; A Pares; J Joven; L Masana; J Rodes
Journal: Clin Sci (Lond) Date: 1992-12 Impact factor: 6.124

5. Glomerular actions of a free radical-generated novel prostaglandin, 8-epi-prostaglandin F2 alpha, in the rat. Evidence for interaction with thromboxane A2 receptors.

Authors: K Takahashi; T M Nammour; M Fukunaga; J Ebert; J D Morrow; L J Roberts; R L Hoover; K F Badr
Journal: J Clin Invest Date: 1992-07 Impact factor: 14.808

6. Thromboxane receptor blockade reduces renal injury in murine lupus nephritis.

Authors: R F Spurney; P Y Fan; P Ruiz; F Sanfilippo; D S Pisetsky; T M Coffman
Journal: Kidney Int Date: 1992-04 Impact factor: 10.612

7. Contribution of platelet thromboxane production to enhanced urinary excretion and glomerular production of thromboxane and to the pathogenesis of albuminuria in the streptozotocin-diabetic rat.

Authors: F R DeRubertis; P A Craven
Journal: Metabolism Date: 1992-01 Impact factor: 8.694