Literature DB >> 18473932

Polyphenols as potential inhibitors of amyloid aggregation and toxicity: possible significance to Alzheimer's disease.

S Bastianetto1, S Krantic, R Quirion.   

Abstract

Beta-amyloid (Abeta)likely plays a pivotal role in the etiology of Alzheimer's disease (AD). Consequently, Abeta associated pathways are targets for the development of possible effective AD therapies. This review first updates strategies aimed at the inhibition of Abeta formation and then discusses the role of food-derived polyphenols as putative anti-amyloid drugs.

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Year:  2008        PMID： 18473932     DOI： 10.2174/138955708784223512

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  16 in total

1.  Aβ(1-42) assembly in the presence of scyllo-inositol derivatives: identification of an oxime linkage as important for the development of assembly inhibitors.

Authors:  J E Shaw; J Chio; S Dasgupta; A Y Lai; G C H Mo; F Pang; L A M Thomason; A J Yang; C M Yip; M Nitz; J McLaurin
Journal:  ACS Chem Neurosci       Date:  2011-12-23       Impact factor: 4.418

2.  Disordered binding of small molecules to Aβ(12-28).

Authors:  Marino Convertino; Andreas Vitalis; Amedeo Caflisch
Journal:  J Biol Chem       Date:  2011-10-03       Impact factor: 5.157

3.  A peptidomimetic approach to targeting pre-amyloidogenic states in type II diabetes.

Authors:  James A Hebda; Ishu Saraogi; Mazin Magzoub; Andrew D Hamilton; Andrew D Miranker
Journal:  Chem Biol       Date:  2009-09-25

4.  Complete phenotypic recovery of an Alzheimer's disease model by a quinone-tryptophan hybrid aggregation inhibitor.

Authors:  Roni Scherzer-Attali; Riccardo Pellarin; Marino Convertino; Anat Frydman-Marom; Nirit Egoz-Matia; Sivan Peled; Michal Levy-Sakin; Deborah E Shalev; Amedeo Caflisch; Ehud Gazit; Daniel Segal
Journal:  PLoS One       Date:  2010-06-14       Impact factor: 3.240

5.  Orally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal models.

Authors:  Anat Frydman-Marom; Aviad Levin; Dorit Farfara; Tali Benromano; Roni Scherzer-Attali; Sivan Peled; Robert Vassar; Daniel Segal; Ehud Gazit; Dan Frenkel; Michael Ovadia
Journal:  PLoS One       Date:  2011-01-28       Impact factor: 3.240

6.  Protective action of resveratrol in human skin: possible involvement of specific receptor binding sites.

Authors:  Stéphane Bastianetto; Yvan Dumont; Albert Duranton; Freya Vercauteren; Lionel Breton; Rémi Quirion
Journal:  PLoS One       Date:  2010-09-23       Impact factor: 3.240

7.  Neuroprotective effects of berry fruits on neurodegenerative diseases.

Authors:  Selvaraju Subash; Musthafa Mohamed Essa; Samir Al-Adawi; Mushtaq A Memon; Thamilarasan Manivasagam; Mohammed Akbar
Journal:  Neural Regen Res       Date:  2014-08-15       Impact factor: 5.135

8.  Oleuropein aglycone protects transgenic C. elegans strains expressing Aβ42 by reducing plaque load and motor deficit.

Authors:  Luisa Diomede; Stefania Rigacci; Margherita Romeo; Massimo Stefani; Mario Salmona
Journal:  PLoS One       Date:  2013-03-08       Impact factor: 3.240

9.  Liuwei Dihuang (LWDH), a traditional Chinese medicinal formula, protects against β-amyloid toxicity in transgenic Caenorhabditis elegans.

Authors:  Jatinder S Sangha; Xiaoli Sun; Owen S D Wally; Kaibin Zhang; Xiuhong Ji; Zhimin Wang; Yanwen Wang; Jeffrey Zidichouski; Balakrishnan Prithiviraj; Junzeng Zhang
Journal:  PLoS One       Date:  2012-08-30       Impact factor: 3.240

10.  Neuroprotective effects of resveratrol and epigallocatechin gallate polyphenols are mediated by the activation of protein kinase C gamma.

Authors:  Caroline Menard; Stéphane Bastianetto; Rémi Quirion
Journal:  Front Cell Neurosci       Date:  2013-12-26       Impact factor: 5.505
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