Literature DB >> 18473924

Carbonyl-scavenging drugs & protection against carbonyl stress-associated cell injury.

P C Burcham1, L M Kaminskas, D Tan, S M Pyke.   

Abstract

This mini-review highlights the chemical and cytoprotective properties of various hydralazine analogues that block the induction of cell death by acrolein, a highly toxic contributor to "carbonyl stress" during a diverse range of human diseases. Recent work on the action of hydralazine against various carbonyl-mediated pathologies is also reviewed.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18473924     DOI： 10.2174/138955708783955953

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  7 in total

1.  Hydralazine modifies Aβ fibril formation and prevents modification by lipids in vitro.

Authors:  Mukesh Maheshwari; Jessica K Roberts; Brent Desutter; Karen T Duong; Joseph Tingling; Janelle N Fawver; Hayley E Schall; Michael Kahle; Ian V J Murray
Journal:  Biochemistry       Date:  2010-11-17       Impact factor: 3.162

2.  Metabolic Investigation on the Interaction Mechanism between Dietary Dihydrochalcone Intake and Lipid Peroxidation Product Acrolein Reduction.

Authors:  Yingdong Zhu; Weixin Wang; Qiju Huang; Changlin Hu; Shengmin Sang
Journal:  Mol Nutr Food Res       Date:  2022-03-03       Impact factor: 6.575

3.  Cigarette smoke component acrolein modulates chromatin assembly by inhibiting histone acetylation.

Authors:  Danqi Chen; Lei Fang; Hongjie Li; Moon-shong Tang; Chunyuan Jin
Journal:  J Biol Chem       Date:  2013-06-14       Impact factor: 5.157

4.  Environmental-stress-induced Chromatin Regulation and its Heritability.

Authors:  Lei Fang; Kenly Wuptra; Danqi Chen; Hongjie Li; Shau-Ku Huang; Chunyuan Jin; Kazunari K Yokoyama
Journal:  J Carcinog Mutagen       Date:  2014-01-15

5.  Müller glial dysfunction during diabetic retinopathy in rats is reduced by the acrolein-scavenging drug, 2-hydrazino-4,6-dimethylpyrimidine.

Authors:  Rosemary E McDowell; Peter Barabas; Josy Augustine; Olivier Chevallier; Philip McCarron; Mei Chen; J Graham McGeown; Tim M Curtis
Journal:  Diabetologia       Date:  2018-08-15       Impact factor: 10.122

Review 6.  The Role of Lipoxidation in the Pathogenesis of Diabetic Retinopathy.

Authors:  Josy Augustine; Evan P Troendle; Peter Barabas; Corey A McAleese; Thomas Friedel; Alan W Stitt; Tim M Curtis
Journal:  Front Endocrinol (Lausanne)       Date:  2021-02-18       Impact factor: 5.555

7.  An overview of pharmacological approaches for management and repair of spinal cord injuries.

Authors:  Alireza Khoshnevisan; Azam Mardani; Shahab Kamali
Journal:  Iran J Psychiatry       Date:  2010
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.