| Literature DB >> 18470811 |
Jun Huo1, Sheng-Ping Yang, Bo-Jun Xie, Shang-Gao Liao, Li-Ping Lin, Jian Ding, Jian-Min Yue.
Abstract
Two new sesquiterpenoids, vernobockolides A (1) and B (2), along with five known ones, piptocarphin C (3), piptocarphin F (4), piptocarphin A (5), hirsutolide (6), and beta-d-glucopyranosyl taraxinic ester (7), were isolated from the aerial part of Vernonia bockiana. Their structures were determined by spectroscopic analysis, especially 2D NMR. Among them, compounds 2-6 showed strong cytotoxic activities against mouse lymphoid tumor cell line P388 with the IC(50) values of 1.81, 1.32, 0.77, and 0.73 microM, respectively.Entities:
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Year: 2008 PMID： 18470811 DOI： 10.1080/10286020801966906
Source DB: PubMed Journal: J Asian Nat Prod Res ISSN： 1028-6020 Impact factor: 1.569