Literature DB >> 18468397

A new diketopiperazine alkaloid isolated from an algicolous Aspergillus flavus strain.

Aiqun Lin1, Yuchun Fang, Tianjiao Zhu, Qianqun Gu, Weiming Zhu.   

Abstract

A new diketopiperazine alkaloid containing the uncommon amino acid L-7, 9-dihydroxy-8-methoxyphenylalanine (1), has been isolated from the algicolous Aspergillus flavus strain. The structure of 1 including the absolute stereochemistry was determined by spectroscopic data and chemical means. Compound 1 showed weak cytotoxicity against HL-60 cell lines with an IC50 value of 36.5 microg/ml.

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Year:  2008        PMID： 18468397

Source DB:  PubMed          Journal:  Pharmazie        ISSN： 0031-7144            Impact factor:   1.267


  4 in total

1.  Biocontrol of Aspergillus species on peanut kernels by antifungal diketopiperazine producing Bacillus cereus associated with entomopathogenic nematode.

Authors:  Sasidharan Nishanth Kumar; Sreerag Ravikumar Sreekala; Dileep Chandrasekaran; Bala Nambisan; Ruby John Anto
Journal:  PLoS One       Date:  2014-08-26       Impact factor: 3.240

2.  Comprehensive Secondary Metabolite Profiling Toward Delineating the Solid and Submerged-State Fermentation of Aspergillus oryzae KCCM 12698.

Authors:  Su Y Son; Sunmin Lee; Digar Singh; Na-Rae Lee; Dong-Yup Lee; Choong H Lee
Journal:  Front Microbiol       Date:  2018-05-25       Impact factor: 5.640

Review 3.  Structural Diversity and Biological Activities of the Cyclodipeptides from Fungi.

Authors:  Xiaohan Wang; Yuying Li; Xuping Zhang; Daowan Lai; Ligang Zhou
Journal:  Molecules       Date:  2017-11-23       Impact factor: 4.411

Review 4.  Cyclic Dipeptides: The Biological and Structural Landscape with Special Focus on the Anti-Cancer Proline-Based Scaffold.

Authors:  Joanna Bojarska; Adam Mieczkowski; Zyta M Ziora; Mariusz Skwarczynski; Istvan Toth; Ahmed O Shalash; Keykavous Parang; Shaima A El-Mowafi; Eman H M Mohammed; Sherif Elnagdy; Maha AlKhazindar; Wojciech M Wolf
Journal:  Biomolecules       Date:  2021-10-14
  4 in total

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