Literature DB >> 18467622

Significance of limb trauma as an initiating factor in chronic leg ulceration.

S R Kulkarni1, M S Gohel, M R Whyman, K R Poskitt.   

Abstract

OBJECTIVES: To assess differences in clinical outcomes between patients with traumatic and spontaneous leg ulcers.
METHODS: Consecutive leg ulcer follow-up patients seen between April 2004 and October 2005 in a specialist leg ulcer clinic were asked about the mechanism of the original ulceration. Twenty-four-week healing and 12-month recurrence rates were calculated using Kaplan-Meier analysis and outcomes were compared between groups with traumatic and spontaneous ulcers.
RESULTS: Of the 300 patients assessed, 38 were excluded (incomplete data). In the remaining 262 patients, cause of ulceration was traumatic in 116/262 (44%) and spontaneous in 146/262 (56%). Age, ankle brachial pressure index <0.85 and venous reflux were equally distributed between groups with traumatic and spontaneous ulcers (P = 0.470, 0.793, 0.965 respectively, Chi-square test). Twenty-four-week healing rates were 81% for traumatic and 67% for spontaneous ulcers (P = 0.015, Log-Rank test). Twelve-month recurrence rates were 32% for traumatic and 33% for spontaneous ulcers (P = 0.970, Log-rank test). Patients with traumatic ulcers suffered a total of 53 ulcer recurrences (median 0, range 0-4) compared with 89 in patients with spontaneous ulcers (median 0, range 0-8) (P < 0.001, Mann-Whitney U test).
CONCLUSION: Approximately half of all leg ulcer patients recall a traumatic event. When managed in leg ulcer clinic, traumatic ulcers heal faster and recur less frequently than spontaneous ulcers.

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Year:  2008        PMID: 18467622     DOI: 10.1258/phleb.2007.007024

Source DB:  PubMed          Journal:  Phlebology        ISSN: 0268-3555            Impact factor:   1.740


  2 in total

1.  Effects of upper-limb exercise on lower-limb cutaneous microvascular function in post-surgical varicose-vein patients.

Authors:  Markos Klonizakis; Garry A Tew; Jonathan A Michaels; John M Saxton
Journal:  Eur J Appl Physiol       Date:  2010-04-10       Impact factor: 3.078

2.  Participant experiences in a feasibility trial of supervised exercise training in adults with venous leg ulcers: A qualitative study.

Authors:  Sue Kesterton; Helen J Crank; Garry A Tew; Jonathan Michaels; Anil Gumber; Emma McIntosh; Brenda King; Markos Klonizakis
Journal:  Int Wound J       Date:  2019-10-13       Impact factor: 3.315

  2 in total

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