Literature DB >> 18466872

Abdominal hernia repair with bridging acellular dermal matrix--an expensive hernia sac.

Jeffrey Blatnik1, Judy Jin, Michael Rosen.   

Abstract

BACKGROUND: The ability of biologic mesh to remodel into native fascia and prevent hernia recurrence in complicated repairs is appealing. However, few long-term data exist evaluating these products in the setting of bridging fascial defects. These collagen-based mesh products are costly, and long-term evaluation of hernia recurrence rates are necessary to justify their expense.
METHODS: This was a retrospective review of patients undergoing repair of complex abdominal defects with acellular dermal matrix (ADM) at our institution was performed.
RESULTS: Between January 2004 and December 2005, 11 patients underwent complex ventral hernia repairs with bridging ADM. Indications for repair included resection of enterocutaneous fistula, infected mesh, and/or ventral hernia repair. A mean of 175 cm(2) (range 8 to 456) of ADM were used. Mean follow-up was 24 months (range 18 to 37). One patient died on postoperative day 20. Eight of the 10 (80%) remaining patients had recurrences, and 7 underwent further surgery for repair. One patient reported laxity but refused repair. The total cost of ADM alone for these 11 patients was $61,926; the cost for the 8 patients having recurrences was $40,776; and the total mean cost was $5,100/patient.
CONCLUSIONS: Although bridging fascial defects with ADM can be an appealing substitute in extremely complicated cases, our data demonstrate exceedingly high recurrence rates. The long-term outcome of bridging fascial defects with biologic prosthesis does not justify the expense of the product.

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Year:  2008        PMID: 18466872     DOI: 10.1016/j.amjsurg.2007.06.035

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


  40 in total

Review 1.  A novel tool to evaluate bias in literature on use of biologic mesh in abdominal wall hernia repair.

Authors:  J Con; L Zarain; S Gogna; D J Samson; K Prabhakaran; S Gashi; E Tilley; R Latifi
Journal:  Hernia       Date:  2019-04-08       Impact factor: 4.739

Review 2.  Incisions and reconstruction approaches for large sarcomas.

Authors:  Leigh J Spera; Rachel M Danforth; Ivan Hadad
Journal:  Transl Gastroenterol Hepatol       Date:  2018-10-31

3.  Not all biologics are equal!

Authors:  B C Shah; M M Tiwari; M R Goede; M J Eichler; R R Hollins; C L McBride; J S Thompson; D Oleynikov
Journal:  Hernia       Date:  2010-12-28       Impact factor: 4.739

4.  Effect of enzymatic degradation on the mechanical properties of biological scaffold materials.

Authors:  Afua H Annor; Michael E Tang; Chi Lun Pui; Gregory C Ebersole; Margaret M Frisella; Brent D Matthews; Corey R Deeken
Journal:  Surg Endosc       Date:  2012-04-27       Impact factor: 4.584

5.  Guidelines for the management of hiatal hernia.

Authors:  Geoffrey Paul Kohn; Raymond Richard Price; Steven R DeMeester; Jörg Zehetner; Oliver J Muensterer; Ziad Awad; Sumeet K Mittal; William S Richardson; Dimitrios Stefanidis; Robert D Fanelli
Journal:  Surg Endosc       Date:  2013-09-10       Impact factor: 4.584

6.  Abdominal wall reconstruction in patients with digestive tract fistulas.

Authors:  Eric K Johnson; Pamela L Tushoski
Journal:  Clin Colon Rectal Surg       Date:  2010-09

Review 7.  Surgical mesh for ventral incisional hernia repairs: Understanding mesh design.

Authors:  Ali Rastegarpour; Michael Cheung; Madhurima Vardhan; Mohamed M Ibrahim; Charles E Butler; Howard Levinson
Journal:  Plast Surg (Oakv)       Date:  2016       Impact factor: 0.947

Review 8.  A primer on wound healing in colorectal surgery in the age of bioprosthetic materials.

Authors:  Jonathan B Lundy
Journal:  Clin Colon Rectal Surg       Date:  2014-12

9.  First human use of hybrid synthetic/biologic mesh in ventral hernia repair: a multicenter trial.

Authors:  James G Bittner; Kevin El-Hayek; Andrew T Strong; Melissa Phillips LaPinska; Jin S Yoo; Eric M Pauli; Matthew Kroh
Journal:  Surg Endosc       Date:  2017-07-19       Impact factor: 4.584

10.  Hernia repair: the search for ideal meshes.

Authors:  S Bringman; J Conze; D Cuccurullo; J Deprest; K Junge; B Klosterhalfen; E Parra-Davila; B Ramshaw; V Schumpelick
Journal:  Hernia       Date:  2009-12-11       Impact factor: 4.739

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