Literature DB >> 18466262

An evidence-based definition of lifelong premature ejaculation: report of the International Society for Sexual Medicine (ISSM) ad hoc committee for the definition of premature ejaculation.

Chris G McMahon1, Stanley E Althof, Marcel D Waldinger, Hartmut Porst, John Dean, Ira D Sharlip, P G Adaikan, Edgardo Becher, Gregory A Broderick, Jacques Buvat, Khalid Dabees, Annamaria Giraldi, François Giuliano, Wayne J G Hellstrom, Luca Incrocci, Ellen Laan, Eric Meuleman, Michael A Perelman, Raymond C Rosen, David L Rowland, Robert Segraves.   

Abstract

INTRODUCTION: The medical literature contains several definitions of premature ejaculation (PE). The most commonly quoted definition, the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition-Text Revision, and other definitions of PE are all authority based rather than evidence based, and have no support from controlled clinical and/or epidemiological studies. AIM: The aim of this article is to develop a contemporary, evidence-based definition of PE.
METHODS: In August 2007, the International Society for Sexual Medicine (ISSM) appointed several international experts in PE to an Ad Hoc Committee for the Definition of Premature Ejaculation. The committee met in Amsterdam in October 2007 to evaluate the strengths and weaknesses of current definitions of PE, to critique the evidence in support of the constructs of ejaculatory latency, ejaculatory control, sexual satisfaction, and personal/interpersonal distress, and to propose a new evidence-based definition of PE.
RESULTS: The committee unanimously agreed that the constructs that are necessary to define PE are rapidity of ejaculation, perceived self-efficacy and control, and negative personal consequences from PE. The committee proposed that lifelong PE be defined as ". . . a male sexual dysfunction characterized by ejaculation which always or nearly always occurs prior to or within about one minute of vaginal penetration, and the inability to delay ejaculation on all or nearly all vaginal penetrations, and negative personal consequences, such as distress, bother, frustration and/or the avoidance of sexual intimacy." This definition is limited to men with lifelong PE who engage in vaginal intercourse. The panel concluded that there are insufficient published objective data to propose an evidence-based definition of acquired PE.
CONCLUSION: The ISSM definition of lifelong PE represents the first evidence-based definition of PE. This definition will hopefully lead to the development of new tools and Patient Reported Outcome measures for diagnosing and assessing the efficacy of treatment interventions and encourage ongoing research into the true prevalence of this disorder and the efficacy of new pharmacological and psychological treatments.

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Year:  2008        PMID: 18466262     DOI: 10.1111/j.1743-6109.2008.00901.x

Source DB:  PubMed          Journal:  J Sex Med        ISSN: 1743-6095            Impact factor:   3.802


  75 in total

Review 1.  New concepts in the diagnosis and treatment of premature ejaculation.

Authors:  Christopher E Keel; Phillip J Dorsey; William Acker; Wayne J G Hellstrom
Journal:  Curr Urol Rep       Date:  2010-11       Impact factor: 3.092

2.  Prevalence of premature ejaculation in young and middle-aged men in Korea: a multicenter internet-based survey from the Korean Andrological Society.

Authors:  Hyun Jun Park; Jong Kwan Park; Kwangsung Park; Sung Won Lee; Sae-Woong Kim; Dae Yul Yang; Du Geon Moon; Kweon-Sik Min; Ki-Hak Moon; Sang-Kuk Yang; Jae Seog Hyun; Nam Cheol Park
Journal:  Asian J Androl       Date:  2010-08-02       Impact factor: 3.285

Review 3.  Advances in understanding and treating premature ejaculation.

Authors:  Theodore R Saitz; Ege Can Serefoglu
Journal:  Nat Rev Urol       Date:  2015-10-27       Impact factor: 14.432

4.  In vitro measurement of ejaculation latency time (ELT) and the effects of vardenafil on ELT on lifelong premature ejaculators: placebo-controlled, double-blind, cross-over laboratory setting.

Authors:  Ahmet Gökçe; Abdullah Demirtas; Fikret Halis; Oguz Ekmekcioglu
Journal:  Int Urol Nephrol       Date:  2010-02-20       Impact factor: 2.370

5.  Does circumcision have a relationship with ejaculation time? Premature ejaculation evaluated using new diagnostic tools.

Authors:  B F Alp; S Uguz; E Malkoc; F Ates; F Dursun; S Okcelik; H Kocoglu; A K Karademir
Journal:  Int J Impot Res       Date:  2014-01-02       Impact factor: 2.896

Review 6.  [Premature ejaculation].

Authors:  H Porst
Journal:  Urologe A       Date:  2009-06       Impact factor: 0.639

Review 7.  Male sexual dysfunction in Asia.

Authors:  Christopher Ck Ho; Praveen Singam; Goh Eng Hong; Zulkifli Md Zainuddin
Journal:  Asian J Androl       Date:  2011-06-06       Impact factor: 3.285

8.  Study of the link between dopamine transporter gene polymorphisms and response to paroxetin and escitalopram in patients with lifelong premature ejaculation.

Authors:  T K Eltonsi; T M Tawfik; L A Rashed; S F GamalEl Din; M A Mahmoud
Journal:  Int J Impot Res       Date:  2017-09-14       Impact factor: 2.896

9.  Somatosensory evoked potentials assess the efficacy of circumcision for premature ejaculation.

Authors:  J-D Xia; H-S Jiang; L-L Zhu; Z Zhang; H Chen; Y-T Dai
Journal:  Int J Impot Res       Date:  2016-05-19       Impact factor: 2.896

10.  Emerging treatments for premature ejaculation: focus on dapoxetine.

Authors:  Wayne J G Hellstrom
Journal:  Neuropsychiatr Dis Treat       Date:  2009-04-08       Impact factor: 2.570

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