Literature DB >> 18465828

Spirocyclic oxetanes: synthesis and properties.

Georg Wuitschik1, Mark Rogers-Evans, Andreas Buckl, Maurizio Bernasconi, Moritz Märki, Thierry Godel, Holger Fischer, Björn Wagner, Isabelle Parrilla, Franz Schuler, Josef Schneider, André Alker, W Bernd Schweizer, Klaus Müller, Erick M Carreira.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18465828     DOI： 10.1002/anie.200800450

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


× No keyword cloud information.
  21 in total

1.  An Oxetane-Based Polyketide Surrogate To Probe Substrate Binding in a Polyketide Synthase.

Authors:  Bryan D Ellis; Jacob C Milligan; Alexander R White; Vy Duong; Pilar X Altman; Lina Y Mohammed; Matthew P Crump; John Crosby; Ray Luo; Christopher D Vanderwal; Shiou-Chuan Tsai
Journal:  J Am Chem Soc       Date:  2018-04-10       Impact factor: 15.419

2.  Gold-catalyzed one-step practical synthesis of oxetan-3-ones from readily available propargylic alcohols.

Authors:  Longwu Ye; Weimin He; Liming Zhang
Journal:  J Am Chem Soc       Date:  2010-06-30       Impact factor: 15.419

3.  Metabolically Stable tert-Butyl Replacement.

Authors:  David Barnes-Seeman; Monish Jain; Leslie Bell; Suzie Ferreira; Scott Cohen; Xiao-Hui Chen; Jakal Amin; Brad Snodgrass; Panos Hatsis
Journal:  ACS Med Chem Lett       Date:  2013-04-22       Impact factor: 4.345

4.  Lowering Lipophilicity by Adding Carbon: AzaSpiroHeptanes, a logD Lowering Twist.

Authors:  Sébastien L Degorce; Michael S Bodnarchuk; James S Scott
Journal:  ACS Med Chem Lett       Date:  2019-07-18       Impact factor: 4.345

5.  A flexible and stereoselective synthesis of azetidin-3-ones through gold-catalyzed intermolecular oxidation of alkynes.

Authors:  Longwu Ye; Weimin He; Liming Zhang
Journal:  Angew Chem Int Ed Engl       Date:  2011-03-04       Impact factor: 15.336

6.  Investigating 3,3-diaryloxetanes as potential bioisosteres through matched molecular pair analysis.

Authors:  Maryne A J Dubois; Rosemary A Croft; Yujie Ding; Chulho Choi; Dafydd R Owen; James A Bull; James J Mousseau
Journal:  RSC Med Chem       Date:  2021-10-06

7.  Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries.

Authors:  Jason T Lowe; Maurice D Lee; Lakshmi B Akella; Emeline Davoine; Etienne J Donckele; Landon Durak; Jeremy R Duvall; Baudouin Gerard; Edward B Holson; Adrien Joliton; Sarathy Kesavan; Berenice C Lemercier; Haibo Liu; Jean-Charles Marié; Carol A Mulrooney; Giovanni Muncipinto; Morgan Welzel-O'Shea; Laura M Panko; Ann Rowley; Byung-Chul Suh; Meryl Thomas; Florence F Wagner; Jingqiang Wei; Michael A Foley; Lisa A Marcaurelle
Journal:  J Org Chem       Date:  2012-08-10       Impact factor: 4.354

8.  Enantioselective intramolecular openings of oxetanes catalyzed by (salen)Co(III) complexes: access to enantioenriched tetrahydrofurans.

Authors:  Rebecca N Loy; Eric N Jacobsen
Journal:  J Am Chem Soc       Date:  2009-03-04       Impact factor: 15.419

Review 9.  Put a ring on it: application of small aliphatic rings in medicinal chemistry.

Authors:  Matthias R Bauer; Paolo Di Fruscia; Simon C C Lucas; Iacovos N Michaelides; Jennifer E Nelson; R Ian Storer; Benjamin C Whitehurst
Journal:  RSC Med Chem       Date:  2021-01-07

10.  Strain-Release Driven Spirocyclization of Azabicyclo[1.1.0]butyl Ketones.

Authors:  Jasper L Tyler; Adam Noble; Varinder K Aggarwal
Journal:  Angew Chem Int Ed Engl       Date:  2021-04-16       Impact factor: 15.336
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.