H Erdol1, M Kola, A Turk, N Akyol. 1. Department of Ophthalmology, Karadeniz Technical University, School of Medicine, Trabzon - Turkey.
Abstract
PURPOSE: Posterior microphthalmos is a rare ocular abnormality. The authors report two siblings with bilateral posterior microphthalmos. METHODS: Two siblings (aged 10 and 13) were admitted with a history of low degree of vision. Ophthalmologic examinations, ocular ultrasonography, ultrasonic biomicroscopy (UBM), and optical coherence tomography (OCT) investigations were carried out and the results were evaluated. All results were also compared with their normal sibling. RESULTS: Two siblings with posterior microphthalmos have normal and near normal anterior segment dimensions, shortened axial lengths (smaller than 17 mm), low vision with high hyperopias, papillomacular folds, and crowded optic discs. OCT investigation showed bilateral papillomacular retinal fold and UBM examination showed that ciliary body moved behind the iris towards the pupilla and the iridocorneal angle anomalies in two siblings. These findings were not observed in the normal sibling. CONCLUSIONS: Posterior microphthalmos can exist in the presence of some ocular anomalies. In this case report, UBM provided new information about the structure of iridocorneal angle and ciliary body.
PURPOSE: Posterior microphthalmos is a rare ocular abnormality. The authors report two siblings with bilateral posterior microphthalmos. METHODS: Two siblings (aged 10 and 13) were admitted with a history of low degree of vision. Ophthalmologic examinations, ocular ultrasonography, ultrasonic biomicroscopy (UBM), and optical coherence tomography (OCT) investigations were carried out and the results were evaluated. All results were also compared with their normal sibling. RESULTS: Two siblings with posterior microphthalmos have normal and near normal anterior segment dimensions, shortened axial lengths (smaller than 17 mm), low vision with high hyperopias, papillomacular folds, and crowded optic discs. OCT investigation showed bilateral papillomacular retinal fold and UBM examination showed that ciliary body moved behind the iris towards the pupilla and the iridocorneal angle anomalies in two siblings. These findings were not observed in the normal sibling. CONCLUSIONS: Posterior microphthalmos can exist in the presence of some ocular anomalies. In this case report, UBM provided new information about the structure of iridocorneal angle and ciliary body.
Authors: Andreas Gal; Isabella Rau; Leila El Matri; Hans-Jürgen Kreienkamp; Susanne Fehr; Karim Baklouti; Ibtissem Chouchane; Yun Li; Monika Rehbein; Josefine Fuchs; Hans C Fledelius; Kaj Vilhelmsen; Daniel F Schorderet; Francis L Munier; Elsebet Ostergaard; Debra A Thompson; Thomas Rosenberg Journal: Am J Hum Genet Date: 2011-03-11 Impact factor: 11.025