Socio-economic deprivation and survival of non-Hodgkin lymphoma in Scotland.

Socio-economic deprivation is known to be associated with poorer survival from non-Hodgkin lymphoma (NHL) but routine data have not been able to determine whether this can be explained by differences in disease severity at presentation. We examined survival in all patients diagnosed with NHL in Scotland between 1979 and 1996 and between 1994 and 1996 used Scotland and Newcastle Lymphoma Group data, which include detailed clinical staging information. Compared with individuals from the most affluent areas, survival is 10% poorer in intermediate, and 19% poorer in patients living in the most deprived areas. Deprivation is associated with more B symptoms and poorer performance status but not with other indicators of more advanced disease, suggesting that the disease may be more aggressive or immunocompetence poorer among more deprived populations. We also noted improvements in relative survival from NHL over time.