| Literature DB >> 18462819 |
Leani Souza Máximo Pereira1, Fabrícia Mendes Silva Narciso, Daniela Matos Garcia Oliveira, Fernanda Matos Coelho, Danielle da Glória de Souza, Rosângela Corrêa Dias.
Abstract
Sarcopenia is a loss of muscle mass related to aging and leads to muscle performance decline. An increase in inflammatory mediator levels, especially of IL-6, has been associated to reduced muscle strength in the elderly. The aim of the present cross-sectional study was to correlate IL-6 plasma levels with manual muscle strength (MMS) in 63 community-dwelling elderly women. (71.2+/-7.4years). IL-6 was measured using enzyme-linked immunosorbent assay (ELISA) and MMS was measured using the JAMAR dynamometer. Pearson's test was used to explore the relationship between the outcomes at the significance level of alpha=0.05. IL-6 levels (2.56+/-3.44pg/ml) and MMS (22.86+/-4.62kgf) exhibited an inverse correlation (r=-0.2673 and p=0.0373). The increase in IL-6 plasma levels possibly contributed toward the reduction in manual muscle strength among the elderly women studied.Entities:
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Year: 2008 PMID： 18462819 DOI： 10.1016/j.archger.2008.02.012
Source DB: PubMed Journal: Arch Gerontol Geriatr ISSN： 0167-4943 Impact factor: 3.250