Literature DB >> 18462003

Synthesis of Bis-18,18'-desmethyl Ritterazine N.

Douglass F Taber1, Jean-Michel Joerger.   

Abstract

Bis-18,18'-desmethyl ritterazine N has been prepared in enantiomerically pure form. The synthetic alkaloid, lacking only two of the 52 carbon atoms of the natural product, shows selective activity in the NIH 60 cell panel.

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Year:  2008        PMID： 18462003     DOI： 10.1021/jo800454w

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  5 in total

Review 1.  Chemistry of trisdecacyclic pyrazine antineoplastics: the cephalostatins and ritterazines.

Authors:  Seongmin Lee; Thomas G LaCour; Philip L Fuchs
Journal:  Chem Rev       Date:  2009-06       Impact factor: 60.622

2.  Ritterostatin GN 1N , a Cephalostatin-Ritterazine Bis-steroidal Pyrazine Hybrid, Selectively Targets GRP78.

Authors:  Andrew J Ambrose; Evelyne A Santos; Paula C Jimenez; Danilo D Rocha; Diego V Wilke; Paolo Beuzer; Josh Axelrod; Ananda Kumar Kanduluru; Philip L Fuchs; Hu Cang; Letícia V Costa-Lotufo; Eli Chapman; James J La Clair
Journal:  Chembiochem       Date:  2017-02-02       Impact factor: 3.164

3.  The cephalostatins. 22. synthesis of bis-steroidal pyrazine pyrones (1).

Authors:  George R Pettit; Bryan R Moser; Ricardo F Mendonça; John C Knight; Fiona Hogan
Journal:  J Nat Prod       Date:  2012-05-18       Impact factor: 4.050

4.  Construction of the tricyclic A-B-C core of the Veratrum alkaloids.

Authors:  Douglass F Taber; James F Berry
Journal:  J Org Chem       Date:  2013-08-06       Impact factor: 4.354

5.  Synthesis of C14,15-dihydro-C22,25-epi north unit of cephalostatin 1 via "red-ox" modifications of hecogenin acetate.

Authors:  Seongmin Lee; Daniel Jamieson; Philip L Fuchs
Journal:  Org Lett       Date:  2009-01-01       Impact factor: 6.005
  5 in total

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