Literature DB >> 18460327

Type 3 deiodinase in hypoxia: to cool or to kill?

Sabrina Diano1, Tamas L Horvath.   

Abstract

Type 3 deiodinase (D3) inactivates thyroid hormones. Simonides et al. (2008) now report that hypoxia-induced D3 activation leads to reduction of 3,5,3'-triiodothyronine (T3) and oxygen consumption, suggesting that D3 activation is a component of cellular responses to hypoxia and supporting the idea of cell-specific regulation of thyroid hormone levels by deiodinases.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18460327     DOI： 10.1016/j.cmet.2008.04.008

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  4 in total

1.  Changes in thyroid hormone receptors after permanent cerebral ischemia in male rats.

Authors:  Athanasios Lourbopoulos; Iordanis Mourouzis; Theodoros Karapanayiotides; Evangelia Nousiopoulou; Stavros Chatzigeorgiou; Theodoros Mavridis; Ioannis Kokkinakis; Olga Touloumi; Theano Irinopoulou; Konstantinos Chouliaras; Constantinos Pantos; Dimitris Karacostas; Nikolaos Grigoriadis
Journal:  J Mol Neurosci       Date:  2014-02-28       Impact factor: 3.444

Review 2.  Thyroid hormones and cardiovascular disease.

Authors:  Avais Jabbar; Alessandro Pingitore; Simon H S Pearce; Azfar Zaman; Giorgio Iervasi; Salman Razvi
Journal:  Nat Rev Cardiol       Date:  2016-11-04       Impact factor: 32.419

3.  Effect of hypothyroidism on contractile performance of isolated end-stage failing human myocardium.

Authors:  Nancy S Saad; Mohammed A Mashali; Mohammad T Elnakish; Austin Hare; Courtney M Campbell; Salome A Kiduko; Kyra K Peczkowski; Amanda W Huang; Farbod Fazlollahi; Gina S Torres Matias; Amany A E Ahmed; Bryan A Whitson; Nahush A Mokadam; Paul M L Janssen
Journal:  PLoS One       Date:  2022-04-11       Impact factor: 3.240

4.  Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy.

Authors:  Mengbo Li; Benjamin L Parker; Evangeline Pearson; Benjamin Hunter; Jacob Cao; Yen Chin Koay; Oneka Guneratne; David E James; Jean Yang; Sean Lal; John F O'Sullivan
Journal:  Nat Commun       Date:  2020-06-02       Impact factor: 14.919
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.