Literature DB >> 18459808

Stereoselective one-pot synthesis of oxazolines.

Saumen Hajra1, Sukanta Bar, Debarshi Sinha, Biswajit Maji.   

Abstract

Treatment of alkenes with NBS, a nitrile, NaHCO3 and water in the presence of Cu(OTf)2 or Zn(OTf)2 is reported to furnish oxazolines in one pot and good yields. The reaction is equally applicable to chalcones.

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Year:  2008        PMID: 18459808     DOI: 10.1021/jo8003937

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  2 in total

1.  Palladium-Catalyzed, Enantioselective Heine Reaction.

Authors:  Molly Punk; Charlotte Merkley; Katlyn Kennedy; Jeremy B Morgan
Journal:  ACS Catal       Date:  2016-06-15       Impact factor: 13.084

2.  Efficient synthesis of ethyl 2-(oxazolin-2-yl)alkanoates via ethoxycarbonylketene-induced electrophilic ring expansion of aziridines.

Authors:  Yelong Lei; Jiaxi Xu
Journal:  Beilstein J Org Chem       Date:  2022-01-05       Impact factor: 2.883

  2 in total

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