Literature DB >> 1845905

Identification of cellular factors that bind specifically to the Epstein-Barr virus origin of DNA replication.

S J Oh1, T Chittenden, A J Levine.   

Abstract

The specific binding of HeLa cell factors to DNA sequences at the Epstein-Barr virus (EBV) latent origin of DNA replication was detected by gel shift experiments and DNase I footprinting analysis. These cellular proteins protected at least five discrete regions of the DNA replication origin. The viral protein required for EBV plasmid replication, EBV nuclear antigen 1 (EBNA-1), binds to specific sequences within the origin region. The HeLa cell proteins competed with EBNA-1 for binding to EBV origin DNA in vitro, leading to the possibility that these cellular proteins regulate EBV DNA replication by displacing EBNA-1 at the origin sites.

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Year:  1991        PMID： 1845905      PMCID： PMC240549     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  18 in total

1.  Covalently closed circular duplex DNA of Epstein-Barr virus in a human lymphoid cell line.

Authors:  T Lindahl; A Adams; G Bjursell; G W Bornkamm; C Kaschka-Dierich; U Jehn
Journal:  J Mol Biol       Date:  1976-04-15       Impact factor: 5.469

2.  Induction of anti-EBNA-1 protein by 12-O-tetradecanoylphorbol-13-acetate treatment of human lymphoblastoid cells.

Authors:  L T Wen; A Tanaka; M Nonoyama
Journal:  J Virol       Date:  1989-08       Impact factor: 5.103

3.  A putative origin of replication of plasmids derived from Epstein-Barr virus is composed of two cis-acting components.

Authors:  D Reisman; J Yates; B Sugden
Journal:  Mol Cell Biol       Date:  1985-08       Impact factor: 4.272

4.  trans activation of an Epstein-Barr viral transcriptional enhancer by the Epstein-Barr viral nuclear antigen 1.

Authors:  D Reisman; B Sugden
Journal:  Mol Cell Biol       Date:  1986-11       Impact factor: 4.272

5.  Replication of the resident repressed Epstein-Barr virus genome during the early S phase (S-1 period) of nonproducer Raji cells.

Authors:  B Hampar; A Tanaka; M Nonoyama; J G Derge
Journal:  Proc Natl Acad Sci U S A       Date:  1974-03       Impact factor: 11.205

6.  DNA sequence and expression of the B95-8 Epstein-Barr virus genome.

Authors:  R Baer; A T Bankier; M D Biggin; P L Deininger; P J Farrell; T J Gibson; G Hatfull; G S Hudson; S C Satchwell; C Séguin
Journal:  Nature       Date:  1984 Jul 19-25       Impact factor: 49.962

7.  Mapping genetic elements of Epstein-Barr virus that facilitate extrachromosomal persistence of Epstein-Barr virus-derived plasmids in human cells.

Authors:  S Lupton; A J Levine
Journal:  Mol Cell Biol       Date:  1985-10       Impact factor: 4.272

8.  Functional limits of oriP, the Epstein-Barr virus plasmid origin of replication.

Authors:  T Chittenden; S Lupton; A J Levine
Journal:  J Virol       Date:  1989-07       Impact factor: 5.103

9.  Electron microscopic evidence for replication of circular Epstein-Barr virus genomes in latently infected Raji cells.

Authors:  E Gussander; A Adams
Journal:  J Virol       Date:  1984-11       Impact factor: 5.103

10.  Identification of Epstein-Barr virus sequences that encode a nuclear antigen expressed in latently infected lymphocytes.

Authors:  J C Hearing; J C Nicolas; A J Levine
Journal:  Proc Natl Acad Sci U S A       Date:  1984-07       Impact factor: 11.205
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  6 in total

1.  Misincorporation rate and type on the leading and lagging strands of UV-damaged DNA.

Authors:  A Calcagnile; T Basic-Zaninovic; F Palombo; E Dogliotti
Journal:  Nucleic Acids Res       Date:  1996-08-01       Impact factor: 16.971

2.  Binding of a sequence-specific single-stranded DNA-binding factor to the simian virus 40 core origin inverted repeat domain is cell cycle regulated.

Authors:  E P Carmichael; J M Roome; A F Wahl
Journal:  Mol Cell Biol       Date:  1993-01       Impact factor: 4.272

3.  Strain-dependent differences in the human cytomegalovirus replication origin.

Authors:  Z Chen; S Watanabe; N Yamaguchi
Journal:  Arch Virol       Date:  1996       Impact factor: 2.574

4.  Identification and functional characterization of the left origin of lytic replication of murine gammaherpesvirus 68.

Authors:  Danyang Gong; Jing Qi; Vaithilingaraja Arumugaswami; Ren Sun; Hongyu Deng
Journal:  Virology       Date:  2009-03-12       Impact factor: 3.616

5.  Cellular protein interactions with herpes simplex virus type 1 oriS.

Authors:  C E Dabrowski; P J Carmillo; P A Schaffer
Journal:  Mol Cell Biol       Date:  1994-04       Impact factor: 4.272

6.  Constitutive binding of EBNA1 protein to the Epstein-Barr virus replication origin, oriP, with distortion of DNA structure during latent infection.

Authors:  D J Hsieh; S M Camiolo; J L Yates
Journal:  EMBO J       Date:  1993-12-15       Impact factor: 11.598
  6 in total

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