Literature DB >> 18458771

Side effects of atypical antipsychotics: a brief overview.

Alp Uçok1, Wolfgang Gaebel.   

Abstract

This paper reviews the available evidence concerning the side effects of atypical antipsychotics, including weight gain, type II diabetes mellitus, hyperlipidemia, QTc interval prolongation, myocarditis, sexual side effects, extrapyramidal side effects and cataract. Some recommendations about how to prevent and manage these side effects are also provided. It is concluded that atypical antipsychotics do not represent a homogeneous class, and that differences in side effects should be taken into account by clinicians when choosing an antipsychotic for an individual patient.

Entities:  

Keywords:  Schizophrenia; atypical antipsychotics; individual treatment; side effects, treatment guidelines

Year:  2008        PMID: 18458771      PMCID: PMC2327229          DOI: 10.1002/j.2051-5545.2008.tb00154.x

Source DB:  PubMed          Journal:  World Psychiatry        ISSN: 1723-8617            Impact factor:   49.548


  46 in total

1.  Early changes of plasma lipids during treatment with atypical antipsychotics.

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Review 2.  Differential metabolic effects of antipsychotic treatments.

Authors:  Dan W Haupt
Journal:  Eur Neuropsychopharmacol       Date:  2006-07-25       Impact factor: 4.600

3.  Prolactin levels and adverse events in patients treated with risperidone.

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Journal:  J Clin Psychopharmacol       Date:  1999-02       Impact factor: 3.153

Review 4.  Management of weight gain in patients with schizophrenia.

Authors:  Ralph Aquila
Journal:  J Clin Psychiatry       Date:  2002       Impact factor: 4.384

5.  Schizophrenia practice guidelines: international survey and comparison.

Authors:  Wolfgang Gaebel; Stefan Weinmann; Norman Sartorius; Wolfgang Rutz; John S McIntyre
Journal:  Br J Psychiatry       Date:  2005-09       Impact factor: 9.319

6.  Risk of diabetes mellitus associated with atypical antipsychotic use among patients with bipolar disorder: A retrospective, population-based, case-control study.

Authors:  Jeff J Guo; Paul E Keck; Patricia K Corey-Lisle; Hong Li; Dongming Jiang; Raymond Jang; Gilbert J L'Italien
Journal:  J Clin Psychiatry       Date:  2006-07       Impact factor: 4.384

Review 7.  Antipsychotic drugs: prolonged QTc interval, torsade de pointes, and sudden death.

Authors:  A H Glassman; J T Bigger
Journal:  Am J Psychiatry       Date:  2001-11       Impact factor: 18.112

Review 8.  [Sexual dysfunction in schizophrenics patients, the role of antipsychotics].

Authors:  Alain Dervaux; Fatima El Omari
Journal:  Presse Med       Date:  2005-04-09       Impact factor: 1.228

9.  The effects of olanzapine, risperidone, and haloperidol on plasma prolactin levels in patients with schizophrenia.

Authors:  S R David; C C Taylor; B J Kinon; A Breier
Journal:  Clin Ther       Date:  2000-09       Impact factor: 3.393

10.  Dosing the antipsychotic medication olanzapine.

Authors:  C B Nemeroff
Journal:  J Clin Psychiatry       Date:  1997       Impact factor: 4.384

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  60 in total

1.  Management of Hyperactive Delirium in the Pediatric Intensive Care Unit: Case Series of Three Young Children.

Authors:  Anna O Jesus; Lotte Jones; Rebecca Linares; Marcia L Buck; Deborah U Frank
Journal:  J Pediatr Intensive Care       Date:  2019-11-21

2.  In male rats, the ability of central insulin to suppress glucose production is impaired by olanzapine, whereas glucose uptake is left intact.

Authors:  Chantel Kowalchuk; Celine Teo; Virginia Wilson; Araba Chintoh; Loretta Lam; Sri Mahavir Agarwal; Adria Giacca; Gary J Remington; Margaret K Hahn
Journal:  J Psychiatry Neurosci       Date:  2017-11       Impact factor: 6.186

3.  International guide to prescribing psychotropic medication for the management of problem behaviours in adults with intellectual disabilities.

Authors:  Shoumitro Deb; Henry Kwok; Marco Bertelli; Luis Salvador-Carulla; Elspeth Bradley; Jennifer Torr; Jarret Barnhill
Journal:  World Psychiatry       Date:  2009-10       Impact factor: 49.548

4.  A comprehensive analysis of mitochondrial genes variants and their association with antipsychotic-induced weight gain.

Authors:  Kirti Mittal; Vanessa F Gonçalves; Ricardo Harripaul; Ari B Cuperfain; Brandi Rollins; Arun K Tiwari; Clement C Zai; Malgorzata Maciukiewicz; Daniel J Müller; Marquis P Vawter; James L Kennedy
Journal:  Schizophr Res       Date:  2017-07-08       Impact factor: 4.939

Review 5.  Classics in Chemical Neuroscience: Aripiprazole.

Authors:  Austen B Casey; Clinton E Canal
Journal:  ACS Chem Neurosci       Date:  2017-04-13       Impact factor: 4.418

6.  Perinatal Generalized Anxiety Disorder: Assessment and Treatment.

Authors:  Shaila Misri; Jasmin Abizadeh; Shawn Sanders; Elena Swift
Journal:  J Womens Health (Larchmt)       Date:  2015-06-30       Impact factor: 2.681

7.  Repurposing antipsychotics as glioblastoma therapeutics: Potentials and challenges.

Authors:  Jin-Ku Lee; DO-Hyun Nam; Jeongwu Lee
Journal:  Oncol Lett       Date:  2016-01-07       Impact factor: 2.967

Review 8.  Antipsychotic induced weight gain: genetics, epigenetics, and biomarkers reviewed.

Authors:  Tahireh A Shams; Daniel J Müller
Journal:  Curr Psychiatry Rep       Date:  2014-10       Impact factor: 5.285

9.  Outpatient antipsychotic drug use in children and adolescents in Germany between 2004 and 2011.

Authors:  Carsten Schröder; Michael Dörks; Bianca Kollhorst; Tilo Blenk; Ralf W Dittmann; Edeltraut Garbe; Oliver Riedel
Journal:  Eur Child Adolesc Psychiatry       Date:  2016-09-13       Impact factor: 4.785

10.  The trace amine theory of spontaneous hypertension as induced by classic monoamine oxidase inhibitors.

Authors:  Vincent Van den Eynde
Journal:  J Neural Transm (Vienna)       Date:  2021-08-09       Impact factor: 3.575

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