Literature DB >> 18458317

The propensity of different Borrelia burgdorferi sensu stricto genotypes to cause disseminated infections in humans.

Daniel E Dykhuizen1, Dustin Brisson, Sabina Sandigursky, Gary P Wormser, John Nowakowski, Robert B Nadelman, Ira Schwartz.   

Abstract

Lineages of Borrelia burgdorferi, the bacterium that causes Lyme disease, can be characterized by distinct alleles at the outer surface protein C (ospC) locus. The lineages marked by ospC genotypes have been shown to be differentially invasive in different species of mammals, including humans; genotypes A, B, I, and K effectively disseminate to human blood and cerebrospinal fluid. In this report, we extend the sample of genotypes isolated from human blood to include genotypes N, H, C, M, and D, and rank each by their probability of disseminating from ticks to the blood of humans. Our results demonstrate that only some genotypes of B. burgdorferi present in ticks have a high propensity to disseminate in humans.

Entities:  

Mesh：

Year:  2008        PMID： 18458317      PMCID： PMC2387051     

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  26 in total

1.  Borrelia burgdorferi ospC heterogeneity among human and murine isolates from a defined region of northern Maryland and southern Pennsylvania: lack of correlation with invasive and noninvasive genotypes.

Authors:  Muneera Y Alghaferi; Jennifer M Anderson; Jinho Park; Paul G Auwaerter; John N Aucott; Douglas E Norris; J Stephen Dumler
Journal:  J Clin Microbiol       Date:  2005-04       Impact factor: 5.948

2.  Demonstration of OspC type diversity in invasive human lyme disease isolates and identification of previously uncharacterized epitopes that define the specificity of the OspC murine antibody response.

Authors:  Christopher G Earnhart; Eric L Buckles; John Stephen Dumler; Richard T Marconi
Journal:  Infect Immun       Date:  2005-12       Impact factor: 3.441

3.  Co-evolution of the outer surface protein C gene (ospC) and intraspecific lineages of Borrelia burgdorferi sensu stricto in the northeastern United States.

Authors:  Oliver Attie; John F Bruno; Yun Xu; Dan Qiu; Benjamin J Luft; Wei-Gang Qiu
Journal:  Infect Genet Evol       Date:  2006-05-08       Impact factor: 3.342

4.  Genetic diversity of Borrelia burgdorferi sensu stricto in Peromyscus leucopus, the primary reservoir of Lyme disease in a region of endemicity in southern Maryland.

Authors:  Jennifer M Anderson; Douglas E Norris
Journal:  Appl Environ Microbiol       Date:  2006-08       Impact factor: 4.792

5.  Association of specific subtypes of Borrelia burgdorferi with hematogenous dissemination in early Lyme disease.

Authors:  G P Wormser; D Liveris; J Nowakowski; R B Nadelman; L F Cavaliere; D McKenna; D Holmgren; I Schwartz
Journal:  J Infect Dis       Date:  1999-09       Impact factor: 5.226

6.  Infection with multiple strains of Borrelia burgdorferi sensu stricto in patients with Lyme disease.

Authors:  G Seinost; W T Golde; B W Berger; J J Dunn; D Qiu; D S Dunkin; D E Dykhuizen; B J Luft; R J Dattwyler
Journal:  Arch Dermatol       Date:  1999-11

7.  A modest model explains the distribution and abundance of Borrelia burgdorferi strains.

Authors:  Dustin Brisson; Daniel E Dykhuizen
Journal:  Am J Trop Med Hyg       Date:  2006-04       Impact factor: 2.345

8.  Interaction and transmission of two Borrelia burgdorferi sensu stricto strains in a tick-rodent maintenance system.

Authors:  Markéta Derdáková; Vladimír Dudiòák; Brandon Brei; John S Brownstein; Ira Schwartz; Durland Fish
Journal:  Appl Environ Microbiol       Date:  2004-11       Impact factor: 4.792

9.  Methods for evaluating Lyme disease risks using geographic information systems and geospatial analysis.

Authors:  M C Nicholson; T N Mather
Journal:  J Med Entomol       Date:  1996-09       Impact factor: 2.278

10.  Epidemic spread of Lyme borreliosis, northeastern United States.

Authors:  Klára Hanincová; Klaus Kurtenbach; Maria Diuk-Wasser; Brandon Brei; Durland Fish
Journal:  Emerg Infect Dis       Date:  2006-04       Impact factor: 6.883
View more
  64 in total

1.  Geographic variation in the relationship between human Lyme disease incidence and density of infected host-seeking Ixodes scapularis nymphs in the Eastern United States.

Authors:  Kim M Pepin; Rebecca J Eisen; Paul S Mead; Joseph Piesman; Durland Fish; Anne G Hoen; Alan G Barbour; Sarah Hamer; Maria A Diuk-Wasser
Journal:  Am J Trop Med Hyg       Date:  2012-06       Impact factor: 2.345

Review 2.  Evolutionary aspects of emerging Lyme disease in Canada.

Authors:  N H Ogden; E J Feil; P A Leighton; L R Lindsay; G Margos; S Mechai; P Michel; T J Moriarty
Journal:  Appl Environ Microbiol       Date:  2015-08-21       Impact factor: 4.792

Review 3.  Evolutionary genomics of Borrelia burgdorferi sensu lato: findings, hypotheses, and the rise of hybrids.

Authors:  Wei-Gang Qiu; Che L Martin
Journal:  Infect Genet Evol       Date:  2014-04-03       Impact factor: 3.342

4.  OspC is potent plasminogen receptor on surface of Borrelia burgdorferi.

Authors:  Özlem Önder; Parris T Humphrey; Brian McOmber; Farida Korobova; Nicholas Francella; Doron C Greenbaum; Dustin Brisson
Journal:  J Biol Chem       Date:  2012-03-20       Impact factor: 5.157

Review 5.  Evolutionary ecology of Lyme Borrelia.

Authors:  Kayleigh R O'Keeffe; Zachary J Oppler; Dustin Brisson
Journal:  Infect Genet Evol       Date:  2020-09-28       Impact factor: 3.342

Review 6.  Evolution and population genomics of the Lyme borreliosis pathogen, Borrelia burgdorferi.

Authors:  Stephanie N Seifert; Camilo E Khatchikian; Wei Zhou; Dustin Brisson
Journal:  Trends Genet       Date:  2015-03-09       Impact factor: 11.639

7.  Differentiation of reinfection from relapse in recurrent Lyme disease.

Authors:  Robert B Nadelman; Klára Hanincová; Priyanka Mukherjee; Dionysios Liveris; John Nowakowski; Donna McKenna; Dustin Brisson; Denise Cooper; Susan Bittker; Gul Madison; Diane Holmgren; Ira Schwartz; Gary P Wormser
Journal:  N Engl J Med       Date:  2012-11-15       Impact factor: 91.245

8.  Borrelia burgdorferi genotype predicts the capacity for hematogenous dissemination during early Lyme disease.

Authors:  Gary P Wormser; Dustin Brisson; Dionysios Liveris; Klára Hanincová; Sabina Sandigursky; John Nowakowski; Robert B Nadelman; Sara Ludin; Ira Schwartz
Journal:  J Infect Dis       Date:  2008-11-01       Impact factor: 5.226

9.  Population structure of the lyme borreliosis spirochete Borrelia burgdorferi in the western black-legged tick (Ixodes pacificus) in Northern California.

Authors:  Yvette A Girard; Bridgit Travinsky; Anna Schotthoefer; Natalia Fedorova; Rebecca J Eisen; Lars Eisen; Alan G Barbour; Robert S Lane
Journal:  Appl Environ Microbiol       Date:  2009-09-25       Impact factor: 4.792

10.  Phylogeography of Borrelia burgdorferi in the eastern United States reflects multiple independent Lyme disease emergence events.

Authors:  Anne Gatewood Hoen; Gabriele Margos; Stephen J Bent; Maria A Diuk-Wasser; Alan Barbour; Klaus Kurtenbach; Durland Fish
Journal:  Proc Natl Acad Sci U S A       Date:  2009-08-14       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.