Literature DB >> 18457227

Bench to bedside: mapping the moral terrain of clinical research.

Steven Joffe, Franklin G Miller.   

Abstract

Medical research is widely thought to have a fundamentally therapeutic orientation, in spite of the fact that clinical research is thought to be ethically distinct from medical care. We need an entirely new conception of clinical research ethics - one that looks to science instead of the doctor-patient relationship.

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Mesh：

Year:  2008        PMID： 18457227     DOI： 10.1353/hcr.2008.0019

Source DB:  PubMed          Journal:  Hastings Cent Rep        ISSN： 0093-0334            Impact factor:   2.683


  36 in total

Review 1.  Equipoise: asking the right questions for clinical trial design.

Authors:  Steven Joffe; Franklin G Miller
Journal:  Nat Rev Clin Oncol       Date:  2012-01-10       Impact factor: 66.675

2.  Deliberate Microbial Infection Research Reveals Limitations to Current Safety Protections of Healthy Human Subjects.

Authors:  David L Evers; Carol B Fowler; Jeffrey T Mason; Rebecca K Mimnall
Journal:  Sci Eng Ethics       Date:  2014-08-24       Impact factor: 3.525

3.  Contextualizing clinical research: the epistemological role of clinical equipoise.

Authors:  James A Anderson
Journal:  Theor Med Bioeth       Date:  2009-04-30

4.  Offering individual genetic research results: context matters.

Authors:  Laura M Beskow; Wylie Burke
Journal:  Sci Transl Med       Date:  2010-06-30       Impact factor: 17.956

5.  Underreporting of Research Biopsies from Clinical Trials in Oncology.

Authors:  Christine M Parseghian; Kanwal Raghav; Robert A Wolff; Joe Ensor; James Yao; Lee M Ellis; Alda L Tam; Michael J Overman
Journal:  Clin Cancer Res       Date:  2017-07-28       Impact factor: 12.531

6.  Ethical issues for control-arm patients after revelation of benefits of experimental therapy: a framework modeled in neuroblastoma.

Authors:  Yoram Unguru; Steven Joffe; Conrad V Fernandez; Alice L Yu
Journal:  J Clin Oncol       Date:  2013-01-07       Impact factor: 44.544

Review 7.  Ethical considerations in tissue engineering research: Case studies in translation.

Authors:  Hannah B Baker; John P McQuilling; Nancy M P King
Journal:  Methods       Date:  2015-08-14       Impact factor: 3.608

8.  The ethics of biosafety considerations in gain-of-function research resulting in the creation of potential pandemic pathogens.

Authors:  Nicholas Greig Evans; Marc Lipsitch; Meira Levinson
Journal:  J Med Ethics       Date:  2015-08-28       Impact factor: 2.903

9.  Recommendations for nanomedicine human subjects research oversight: an evolutionary approach for an emerging field.

Authors:  Leili Fatehi; Susan M Wolf; Jeffrey McCullough; Ralph Hall; Frances Lawrenz; Jeffrey P Kahn; Cortney Jones; Stephen A Campbell; Rebecca S Dresser; Arthur G Erdman; Christy L Haynes; Robert A Hoerr; Linda F Hogle; Moira A Keane; George Khushf; Nancy M P King; Efrosini Kokkoli; Gary Marchant; Andrew D Maynard; Martin Philbert; Gurumurthy Ramachandran; Ronald A Siegel; Samuel Wickline
Journal:  J Law Med Ethics       Date:  2012       Impact factor: 1.718

Review 10.  The clinical investigator-subject relationship: a contextual approach.

Authors:  David B Resnik
Journal:  Philos Ethics Humanit Med       Date:  2009-12-03       Impact factor: 2.464
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