| Literature DB >> 18455979 |
Abstract
Calcium/calmodulin-dependent protein kinase II (CaMKII) is a pivotal signaling molecule in both the brain and the heart. In this issue of Cell, Erickson et al. (2008) demonstrate a mechanism for CaMKII activation by reactive oxygen species that provides a direct link between kinase activation and cardiac dysfunction.Entities:
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Year: 2008 PMID: 18455979 PMCID: PMC2655315 DOI: 10.1016/j.cell.2008.04.018
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582