OBJECTIVE: The purpose of this study was to corroborate the association between obstructive sleep apnea (OSA) and nocturia in a clinical sample of urogynecologic patients and to explore whether night-time urine concentration predicts the presence of OSA. STUDY DESIGN: Patients with nocturia and control subjects underwent a home sleep study, completed validated nocturia questionnaires, and provided evening and morning urine specimens that were analyzed for osmolarity. RESULTS: Twenty-one patients with nocturia (16 of whom also had daytime overactive bladder [OAB] symptoms) and 10 control subjects were studied. OSA was present in 17 of 21 women (81%) with nocturia: 13 women (81%) with OAB, 4 women (80%) with nocturia/no OAB, and 4 control subjects (40%; P < .001). The percentage of rapid eye movement sleep time was correlated inversely with nocturic frequency (rho = -.51; P < .004). The presence of diluted nighttime urine in a patient with nocturia was 88% sensitive for the presence of OSA. CONCLUSION: We should consider a diagnosis of OSA in all patients with nocturia, even those patients with daytime OAB.
OBJECTIVE: The purpose of this study was to corroborate the association between obstructive sleep apnea (OSA) and nocturia in a clinical sample of urogynecologic patients and to explore whether night-time urine concentration predicts the presence of OSA. STUDY DESIGN:Patients with nocturia and control subjects underwent a home sleep study, completed validated nocturia questionnaires, and provided evening and morning urine specimens that were analyzed for osmolarity. RESULTS: Twenty-one patients with nocturia (16 of whom also had daytime overactive bladder [OAB] symptoms) and 10 control subjects were studied. OSA was present in 17 of 21 women (81%) with nocturia: 13 women (81%) with OAB, 4 women (80%) with nocturia/no OAB, and 4 control subjects (40%; P < .001). The percentage of rapid eye movement sleep time was correlated inversely with nocturic frequency (rho = -.51; P < .004). The presence of diluted nighttime urine in a patient with nocturia was 88% sensitive for the presence of OSA. CONCLUSION: We should consider a diagnosis of OSA in all patients with nocturia, even those patients with daytime OAB.
Authors: Daniele Furtado; Helena Hachul; Monica L Andersen; Rodrigo A Castro; Manoel B Girão; Sergio Tufik Journal: Int Urogynecol J Date: 2011-08-17 Impact factor: 2.894
Authors: Nancy S Redeker; Laura Adams; Robert Berkowitz; Lenore Blank; Ronald Freudenberger; Michele Gilbert; Joyce Walsleben; Mark J Zucker; David Rapoport Journal: J Card Fail Date: 2012-07 Impact factor: 5.712
Authors: Emily S Lukacz; Emily L Whitcomb; Jean M Lawrence; Charles W Nager; Karl M Luber Journal: Am J Obstet Gynecol Date: 2009-02-27 Impact factor: 8.661
Authors: Kari A O Tikkinen; Anssi Auvinen; Theodore M Johnson; Jeffrey P Weiss; Tapani Keränen; Aila Tiitinen; Olli Polo; Markku Partinen; Teuvo L J Tammela Journal: Am J Epidemiol Date: 2009-06-10 Impact factor: 4.897
Authors: Lisa L Abler; Chelsea A O'Driscoll; Sara A Colopy; Kimberly P Keil Stietz; Peiqing Wang; Zunyi Wang; Faye Hartmann; Stephanie M Crader-Smith; Jonathan N Oellete; Vatsal Mehta; Steven R Oakes; Matthew D Grimes; Gordon S Mitchell; Mieke Baan; Shannon J Gallagher; Dawn B Davis; Michelle E Kimple; Dale E Bjorling; Jyoti J Watters; Chad M Vezina Journal: Am J Physiol Renal Physiol Date: 2021-06-14