BACKGROUND: Adult-onset foveomacular vitelliform dystrophy (AOFVD) is typically bilateral and symmetrical. We present the spectral optical coherence tomography (OCT) findings in two patients with unilateral AOFVD. PATIENTS AND METHODS: Case 1 represents a 76-year-old man followed angiographically over the last 6 years for a macular lesion in his right eye. Visual acuity in the right eye has decreased from 1.0 to 0.6. In case 2, a 69-year-old man presented with blurred vision in his right eye. Visual acuity was 0.7 in the right eye and 1.0 in the left eye. In both patients, spectral OCT (Copernicus SOCT System) was performed. RESULTS: In case 1, fluorescein angiography showed a juxtafoveal hyperfluorescent lesion 2 / 3 of disc area in size, without late leakage. OCT showed a cystic oval lesion with thick walls, located between the retinal pigment epithelium (RPE) and photoreceptor layers. In case 2, OCT showed a hyperreflective round lesion also located between the RPE and photoreceptor layers, elevating the overlying inner retina. CONCLUSIONS: Spectral OCT enables enhanced visualization of the retinal layers and provides useful information regarding the diagnosis and the exact location of AOFVD.
BACKGROUND: Adult-onset foveomacular vitelliform dystrophy (AOFVD) is typically bilateral and symmetrical. We present the spectral optical coherence tomography (OCT) findings in two patients with unilateral AOFVD. PATIENTS AND METHODS: Case 1 represents a 76-year-old man followed angiographically over the last 6 years for a macular lesion in his right eye. Visual acuity in the right eye has decreased from 1.0 to 0.6. In case 2, a 69-year-old man presented with blurred vision in his right eye. Visual acuity was 0.7 in the right eye and 1.0 in the left eye. In both patients, spectral OCT (Copernicus SOCT System) was performed. RESULTS: In case 1, fluorescein angiography showed a juxtafoveal hyperfluorescent lesion 2 / 3 of disc area in size, without late leakage. OCT showed a cystic oval lesion with thick walls, located between the retinal pigment epithelium (RPE) and photoreceptor layers. In case 2, OCT showed a hyperreflective round lesion also located between the RPE and photoreceptor layers, elevating the overlying inner retina. CONCLUSIONS: Spectral OCT enables enhanced visualization of the retinal layers and provides useful information regarding the diagnosis and the exact location of AOFVD.