[Diagnostic and therapeutic policy in nosocomial sinusitis in intensive care units of a large general hospital].

The study of 60 patients with nosocomial sinusitis (NS) admitted to critical care units of a large general hospital revealed that NS etiology was polybacterial in 42 (70%) cases and monobacterial in 18 (30%) patients. In early NS bacterial associations prevailed (79%), while in late NS monoculture gained more importance (from 21% to 38%). Species microflora was represented in 40 (65%) patients with polyresistent flora. Bacterial sensitivity enabled the authors to develop algorithm of empiric and etiological antibacterial therapy of NS. This algorithm was used in analysis of current practice of NS treatment in critical care units of a large general hospital. In empirical antibacterial therapy of NS effective treatment was given to 32 (53.3%) patients, uneffective - to 28 (46.7%) patients. After obtaining data on sensitivity 70% examinees received adequate antibacterial treatment. Etiopathogenic link of late nosocomial pneumonia with NS was suggested in 23 (59%) patients.