| Literature DB >> 18453698 |
Akiko Shimizu-Ibuka1, Cédric Bauvois, Hiroshi Sakai, Moreno Galleni.
Abstract
The crystallographic structure of ACT-1, which is the first plasmid-mediated AmpC-type beta-lactamase to have been completely analyzed in terms of nucleotide sequence and which has a high degree of sequence similarity to the chromosomal AmpC enzymes of Enterobacter cloacae and the plasmid-encoded MIR-1, has been solved at 2.4 A resolution. The overall structure of ACT-1 is similar to those of other class C beta-lactamases, such as the AmpC enzymes from E. cloacae P99 and Escherichia coli.Entities:
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Year: 2008 PMID: 18453698 PMCID: PMC2376412 DOI: 10.1107/S1744309108008531
Source DB: PubMed Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun ISSN: 1744-3091