Literature DB >> 18453510

Herba Artemisiae annuae tea preparation compared to sulfadoxine-pyrimethamine in the treatment of uncomplicated falciparum malaria in adults: a randomized double-blind clinical trial.

Christoph H Blanke1, Godson B Naisabha, Mussa B Balema, Godfrey M Mbaruku, Lutz Heide, Markus S Müller.   

Abstract

Tea preparations from the herb Artemisia annua L. (Aa) which is used in traditional Chinese medicine might offer an inexpensive way of producing artemisinin drugs locally. We compared Aa with sulfadoxine-pyrimethamine (SP) in the treatment of uncomplicated falciparum malaria in semi-immune adults. After seven days, the cure rate was 7/10 for the Aa compared to 7/9 for SP; this dropped to 4/10 for Aa and 4/9 for SP at day 14 and to 1/9 for Aa and 3/8 for SP at day 28.

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Year:  2008        PMID： 18453510     DOI： 10.1258/td.2007.060184

Source DB:  PubMed          Journal:  Trop Doct        ISSN： 0049-4755            Impact factor:   0.731


  10 in total

1.  Dried-leaf Artemisia annua: A practical malaria therapeutic for developing countries?

Authors:  Pamela J Weathers; Melissa Towler; Ahmed Hassanali; Pierre Lutgen; Patrick Ogwang Engeu
Journal:  World J Pharmacol       Date:  2014-12-09

Review 2.  Discovery, mechanisms of action and combination therapy of artemisinin.

Authors:  Liwang Cui; Xin-zhuan Su
Journal:  Expert Rev Anti Infect Ther       Date:  2009-10       Impact factor: 5.091

Review 3.  Natural products as starting points for future anti-malarial therapies: going back to our roots?

Authors:  Timothy N C Wells
Journal:  Malar J       Date:  2011-03-15       Impact factor: 2.979

4.  The Relationship between Traditional Chinese Medicine and Modern Medicine.

Authors:  Jingcheng Dong
Journal:  Evid Based Complement Alternat Med       Date:  2013-07-30       Impact factor: 2.629

5.  Treatment of Iron-Loaded Veterinary Sarcoma by Artemisia annua.

Authors:  Elmar Breuer; Thomas Efferth
Journal:  Nat Prod Bioprospect       Date:  2014-04-12

6.  Anti-inflammatory effect of Artemisiae annuae herba in lipopolysaccharide-stimulated RAW 264.7 Cells.

Authors:  You-Chang Oh; Yun Hee Jeong; Taesoo Kim; Won-Kyung Cho; Jin Yeul Ma
Journal:  Pharmacogn Mag       Date:  2014-08       Impact factor: 1.085

Review 7.  Antimalarial Plants Used across Kenyan Communities.

Authors:  Timothy Omara
Journal:  Evid Based Complement Alternat Med       Date:  2020-06-12       Impact factor: 2.629

8.  Ancient Chinese methods are remarkably effective for the preparation of artemisinin-rich extracts of Qing Hao with potent antimalarial activity.

Authors:  Colin W Wright; Peter A Linley; Reto Brun; Sergio Wittlin; Elisabeth Hsu
Journal:  Molecules       Date:  2010-02-04       Impact factor: 4.411

9.  Artemisia annua and Artemisia afra tea infusions vs. artesunate-amodiaquine (ASAQ) in treating Plasmodium falciparum malaria in a large scale, double blind, randomized clinical trial.

Authors:  Jérôme Munyangi; Lucile Cornet-Vernet; Michel Idumbo; Chen Lu; Pierre Lutgen; Christian Perronne; Nadège Ngombe; Jacques Bianga; Bavon Mupenda; Paul Lalukala; Guy Mergeai; Dieudonné Mumba; Melissa Towler; Pamela Weathers
Journal:  Phytomedicine       Date:  2018-12-05       Impact factor: 5.340

10.  Comparative cytotoxicity of artemisinin and cisplatin and their interactions with chlorogenic acids in MCF7 breast cancer cells.

Authors:  John O Suberu; Isolda Romero-Canelón; Neil Sullivan; Alexei A Lapkin; Guy C Barker
Journal:  ChemMedChem       Date:  2014-09-10       Impact factor: 3.466
  10 in total

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