| Literature DB >> 18451975 |
Paul M Lundquist1, Cheng F Zhong, Peiqian Zhao, Austin B Tomaney, Paul S Peluso, John Dixon, Brad Bettman, Yves Lacroix, Deborah P Kwo, Etienne McCullough, Mark Maxham, Kevin Hester, Paul McNitt, Donald M Grey, Carlos Henriquez, Mathieu Foquet, Stephen W Turner, Denis Zaccarin.
Abstract
The confocal detection principle is extended to a highly parallel optical system that continuously analyzes thousands of concurrent sample locations. This is achieved through the use of a holographic laser illumination multiplexer combined with a confocal pinhole array before a prism dispersive element used to provide spectroscopic information from each confocal volume. The system is demonstrated to detect and identify single fluorescent molecules from each of several thousand independent confocal volumes in real time.Mesh：
Substances：
Year: 2008 PMID： 18451975 DOI： 10.1364/ol.33.001026
Source DB: PubMed Journal: Opt Lett ISSN： 0146-9592 Impact factor: 3.776