BACKGROUND AND PURPOSE: We assessed the association of prestroke comorbidities with long-term stroke outcomes among women with ischemic stroke. METHODS: Prestroke comorbid conditions in 133 women admitted with acute ischemic stroke were scored with the Charlson Index (CI). We assessed whether the CI and other specific conditions were associated with modified Rankin Score (mRS) at 90 days or more poststroke. RESULTS: After adjustment for initial NIHSS and age, higher CI was the sole factor independently associated with poorer 90 day mRS scores. When CI was excluded, coronary disease and diabetes were independently associated with poorer outcome. CONCLUSIONS: The extent of comorbidities as assessed by the CI is independently associated with 90-day mRS among women with ischemic stroke, but the individual comorbidities of CHD and DM were each associated with functional outcome.
BACKGROUND AND PURPOSE: We assessed the association of prestroke comorbidities with long-term stroke outcomes among women with ischemic stroke. METHODS: Prestroke comorbid conditions in 133 women admitted with acute ischemic stroke were scored with the Charlson Index (CI). We assessed whether the CI and other specific conditions were associated with modified Rankin Score (mRS) at 90 days or more poststroke. RESULTS: After adjustment for initial NIHSS and age, higher CI was the sole factor independently associated with poorer 90 day mRS scores. When CI was excluded, coronary disease and diabetes were independently associated with poorer outcome. CONCLUSIONS: The extent of comorbidities as assessed by the CI is independently associated with 90-day mRS among women with ischemic stroke, but the individual comorbidities of CHD and DM were each associated with functional outcome.
Authors: Moira K Kapral; Jiming Fang; Michael D Hill; Frank Silver; Janice Richards; Cheryl Jaigobin; Angela M Cheung Journal: Stroke Date: 2005-02-24 Impact factor: 7.914
Authors: F Grodstein; M J Stampfer; J E Manson; G A Colditz; W C Willett; B Rosner; F E Speizer; C H Hennekens Journal: N Engl J Med Date: 1996-08-15 Impact factor: 91.245
Authors: Susan L Hendrix; Sylvia Wassertheil-Smoller; Karen C Johnson; Barbara V Howard; Charles Kooperberg; Jacques E Rossouw; Maurizio Trevisan; Aaron Aragaki; Alison E Baird; Paul F Bray; Julie E Buring; Michael H Criqui; David Herrington; John K Lynch; Stephen R Rapp; James Torner Journal: Circulation Date: 2006-05-15 Impact factor: 29.690
Authors: Antonio Di Carlo; Maria Lamassa; Marzia Baldereschi; Giovanni Pracucci; Anna Maria Basile; Charles D A Wolfe; Maurice Giroud; Anthony Rudd; Augusto Ghetti; Domenico Inzitari Journal: Stroke Date: 2003-04-10 Impact factor: 7.914
Authors: Nathalie Percie du Sert; Alessio Alfieri; Stuart M Allan; Hilary Vo Carswell; Graeme A Deuchar; Tracy D Farr; Paul Flecknell; Lindsay Gallagher; Claire L Gibson; Michael J Haley; Malcolm R Macleod; Barry W McColl; Christopher McCabe; Anna Morancho; Lawrence Df Moon; Michael J O'Neill; Isabel Pérez de Puig; Anna Planas; C Ian Ragan; Anna Rosell; Lisa A Roy; Kathryn O Ryder; Alba Simats; Emily S Sena; Brad A Sutherland; Mark D Tricklebank; Rebecca C Trueman; Lucy Whitfield; Raymond Wong; I Mhairi Macrae Journal: J Cereb Blood Flow Metab Date: 2017-08-11 Impact factor: 6.200